2022–23 UAE Division One is the 46th Division one season. This seasons will expand the league from 15 to 17 teams as more teams from UAE Second Division League got promoted to the league.
All teams could register as many foreign players as they want, but could only use two on the field each game.
Players name in bold indicates the player is registered during the mid-season transfer window.
Players in italics were out of the squad or left the club within the season, after the pre-season transfer window, or in the mid-season transfer window, and at least had one appearance.
Source: soccerway Legend: Blue = home team win; Yellow = draw; Red = away team win. For upcoming matches, an "a" indicates there is an article about the rivalry between the two participants.
^The UAE FA rewarded Fujairah a 3–0 win due to Al Hamriyah violating the substitution rule. The match originally ended as a 1–1 draw.[17]
^The UAE FA rewarded Hatta a 3–0 win due to Al Urooba fielding an ineligible player in the field. The match originally ended as a 0–1 victory for Al Urooba.[18]