Sefpirom

Sefpirom
Nama sistematis (IUPAC)
1-{[(6R,7R)-7-[(2E)-2-(2-amino-1,3-tiazol-4-il)-2-(metoksiimino)asetamido]-2-karboksilato-8-okso-5-tia-1-azabisiklo[4.2.0]okt-2-en-3-il]metil}-5H,6H,7H siklopenta[b]piridin-1-ium
Data klinis
Nama dagang Cefrom, Keiten, Broact, dan Cefir
AHFS/Drugs.com International Drug Names
Kat. kehamilan ?
Status hukum ?
Pengenal
Nomor CAS 84957-29-9 YaY
Kode ATC J01DE02
PubChem CID 6917674
ChemSpider 23089536 N
UNII S72Q2F09HY YaY
KEGG D07649 YaY
ChEMBL CHEMBL2106076 N
Data kimia
Rumus C22H22N6O5S2 
SMILES eMolecules & PubChem
  • InChI=1S/C22H22N6O5S2/c1-33-26-15(13-10-35-22(23)24-13)18(29)25-16-19(30)28-17(21(31)32)12(9-34-20(16)28)8-27-7-3-5-11-4-2-6-14(11)27/h3,5,7,10,16,20H,2,4,6,8-9H2,1H3,(H3-,23,24,25,29,31,32)/b26-15-/t16-,20+/m1/s1 N
    Key:DKOQGJHPHLTOJR-XECLGWKCSA-N N

Sefpirom adalah antibiotik sefalosporin generasi keempat. Sefpirom dianggap sangat aktif melawan bakteri Gram-negatif termasuk Pseudomonas aeruginosa, dan bakteri Gram-positif.

Spektrum kerentanan dan resistensi bakteri

Bacteroides fragilis, Enterococcus, Pseudomonas spp., dan Staphylococcus resisten terhadap Sefpirom sulfat; serta beberapa Haemophilus spp. dan Pneumococcus telah mengembangkan resistensi terhadapnya pada tingkat yang berbeda-beda.[1]

Referensi

  1. ^ "Cefpirome Sulfate spectrum of bacterial susceptibility and Resistance" (PDF). Diarsipkan dari versi asli (PDF) tanggal 3 March 2016. Diakses tanggal 10 April 2012. 

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