土克甾酮

Turkesterone
识别信息
  • (2S,3R,5R,9R,10R,11R,13R,14S,17S)-2,3,11,14-tetrahydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one
CAS号41451-87-0  checkY
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)
化学信息
化学式C27H44O8
摩尔质量496.64 g·mol−1
3D模型（JSmol（英语：JSmol））
  • C[C@]12C[C@H]([C@H]3C(=CC(=O)[C@H]4[C@@]3(C[C@@H]([C@@H](C4)O)O)C)[C@@]1(CC[C@@H]2[C@](C)([C@@H](CCC(C)(C)O)O)O)O)O
  • InChI=1S/C27H44O8/c1-23(2,33)8-7-21(32)26(5,34)20-6-9-27(35)15-11-16(28)14-10-17(29)18(30)12-24(14,3)22(15)19(31)13-25(20,27)4/h11,14,17-22,29-35H,6-10,12-13H2,1-5H3/t14-,17+,18-,19+,20-,21+,22+,24-,25+,26+,27+/m0/s1
  • Key:WSBAGDDNVWTLOM-XHZKDPLLSA-N

土克甾酮（英語：Turkesterone）是一种植物蜕皮类固醇，存在于新疆筋骨草（英语：Ajuga turkestanica）（Ajuga turkestanica）[1]、牡荆属（Vitex）[2]、祈州漏卢属（Rhaponticum）[3]等多种植物中，作为毒素或拒食剂来对抗植食性昆虫[4]。大鼠实验表明土克甾酮无同化類固醇效应[5]。

参考文献

  1. ^ Guibout L, Mamadalieva N, Balducci C, Girault JP, Lafont R. The minor ecdysteroids from Ajuga turkestanica (PDF). Phytochemical Analysis. 2015, 26 (5): 293–300 [2022-08-06]. PMID 25953625. doi:10.1002/pca.2563. （原始内容存档 (PDF)于2022-01-07）. 
  2. ^ dos Santos TC, Delle Monache F, Leitão SG. Ecdysteroids from two Brazilian Vitex species. Fitoterapia. March 2001, 72 (3): 215–220. PMID 11295296. doi:10.1016/s0367-326x(00)00304-x. 
  3. ^ Zughdani M, Yusufoğlu HS, Ekiz G, Linden A, Çalış İ. Ecdysteroids from the underground parts of Rhaponticum acaule (L.) DC (PDF). Phytochemistry. December 2020, 180: 112530. PMID 33049649. S2CID 222353903. doi:10.1016/j.phytochem.2020.112530. 
  4. ^ Dinan L. Phytoecdysteroids: biological aspects. Phytochemistry. 2001, 57 (3): 325–339. PMID 11393511. doi:10.1016/S0031-9422(01)00078-4. 
  5. ^ Syrov VN. [Mechanism of the anabolic action of phytoecdisteroids in mammals]. Nauchnye Doklady Vysshei Shkoly. Biologicheskie Nauki. 1984, (11): 16–20. PMID 6525371. 

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