The aminoglycosides are the mainstay in the treatment of serious gram-negative systemic mfections. These are the broad spectrum antibiotics, and could be used for many infections of body systems. A disadvantage of theaminoglycosides is their association with nephrotoxicity, ototoxicity, and neurotoxicity, all are associated with elevated serum levels. This article is carried out to give informations about mechanisms of toxicities and their pathology, which is highlighted on aspects of biochemistry, functional, and structural.

Published by Universitas Islam Indonesia
Journal Name JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
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Location Kab. sleman, Daerah istimewa yogyakarta INDONESIA
Website JKKI| http://journal.uii.ac.id/index.php/JKKI|
ISSN ISSN : 20854145, EISSN : 25272950, DOI : -,
Core Subject Health, Science,
Meta Subject Biochemistry, Genetics & Molecular Biology, Immunology & microbiology, Medicine & Pharmacology, Public Health,
Meta DescJurnal Kedokteran dan Kesehatan Indonesia is the English language based scientific periodical journal, managed by the Faculty of Medicine, Islamic University of Indonesia. It publishes one issue, three times a year. This journal is designed as a place of dissemination of information and scientific knowledge. It publishes literature study, case study, research articles in following fields: (1) Biomedical Sciences; (2) Clinical medicine (Neurology, Cardiovascular, Respiratory, Gastrointestinal, urogenital, Endocrine and Metabolism, Integument, Mental Health, Reproduction, Hematology, Oncology, Musculoskeletal); (3) Public health sciences; (4) Medical Science Education.
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Publisher ArticleFaculty of Medicine
Subtitle Article JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 2, No 5, (2010)
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