This study aims to determine the potency of CV 12 acupuncture as prevention of weight gain in ovariectomizedmice (OVX). Female mice strain BALB/c, 28 mice, 3-4 weeks, 25-35 grams were divided into four groups; namely K1 (n = 8, sham and vehiculum injection), K2 (n = 8, OVX and vehiculum injection), K3 (n = 7, OVX and injection of estrogen intraperitoneal 10 mg/kg/day) and K4 (n = 6, OVX and CV12 acupuncture with a frequency of 2 Hz in 10 mA of continuous spike current wave).Injection and acupuncture given every day for four weeks. Weight change in K1 (0.75 ± 2.8) grams, K2 (2.71 ± 2.4) grams, K3 (0.71 ± 0.95) g and K4 (0.93 ± 2.40) gram with a significant difference in the K2 and K4 (p = 0.011). a receptor expression in K1 (12.25 ± 2.96), K2 (5.43 ± 2.64), K3 (18.86 ± 1.57), K4 (17 ± 2.00) with a significant difference to the K2 K1, K3 and K4 with p<0.05. b receptor expression in K1 (11.38 ± 1.92), K2 (4 ± 1.41), K3 (16.86 ± 1.86), K4 (14.17 ± 5.24) with significantly different a receptor expression in visceral fat mass on the group K2 to K1, K3 and K4 with p<0.05. CV 12 acupuncture increases the expression of a and b estrogen receptor in visceral adipose tissue of OVX mice equivalently and able to prevent the increase of weight due to the estrogen withdrawal. This point could potentially be used as one of the management ofobesity prevention in menopause.
| Published by | Universitas Airlangga |
| Journal Name | Folia Medica Indonesiana |
| Contact Phone | - |
| Contact Name | - |
| Contact Email | - |
| Location | Kota surabaya, Jawa timur INDONESIA |
| Website | FMI| https://e-journal.unair.ac.id/index.php/FMI| |
| ISSN | ISSN : 23558393, EISSN : 2599056X, DOI : -, |
| Core Subject | Education, |
| Meta Subject | Other, |
| Meta Desc | Folia Medica Indonesiana publishes articles in the field of medical science in particular and health sciences in general, as well as a variety of other fields related to those two disciplines. Most of the articles are research article, and others are articles on case reports and literature review. In their presentation in the journal, the articles have passed meticulous editing process by the editors and review process and by competent peer reviewers, with national and international reputation, making the articles presented in this journal qualified, updated, and informative. |
| Penulis | Rejeki, Purwo Sri , Wiyasihati, Sundari Indah , Atika, Atika |
| Publisher Article | Faculty of Medicine, Universitas Airlangga |
| Subtitle Article | Folia Medica Indonesiana Vol 53, No 1 (2017): JANUARY - MARCH 2017 |
| Scholar Google | http://scholar.google.com/scholar?q=%2Bintitle%3A&… |
| View Article | http://e-journal.unair.ac.id/F… |
| DOI | https://doi.org/10.20473/fmi.v53i1.… |
| DOI Number | DOI: 10.20473/fmi.v53i1.5496 |
| Download Article [1] | http://e-journal.unair.ac.id/FMI/article… |
| Download Article [2] | http://download.garuda.ristekdikti.go.id… |
Informasi yang terkait dengan POTENCY OF CV12 ACUPUNCTURE AS OBESITY PREVENTION THROUGH MODULATION OF ï¡ AND ï¢ ESTROGEN RECEPTORS EXPRESSION ON THE ADIPOSE TISSUE OF OVARIECTOMIZED MICE