Valproate is the most common drug to use in bipolar disorder in Indonesia and the only mood stabilizer drug in national formulary. Combination of valproate and fluoxetine are the most used combination in bipolar disorder therapy in Bhayangkara Hospital, Kediri. However, this combination has been controversial because of its risk of triggering mania or hipomania episode in 12 months. The aim of this study was to analyze mood change symptoms with YMRS and MADRS scale after treatment of valproate and fluoxetine combination in continuation phase treatment of bipolar disorder. This cross-sectional, observational study was conducted in psyciatry clinic in Bhayangkara Hospital Kediri between August 2016-October 2016 on 15 patients in YMRS. MADRS questionnaire was filled by physician before treatment and after 8 weeks treatments. Within 8 weeks, mean YMRS score changed from 1.4 to 1.26 (p>0.05). Whereas, mean MADRS score changed from 31.8 to 10.93 (p<0.05) after 8 weeks. There was no significant different in YMRS score between pre- and post-treatment, but there was significant different in MADRS score after treatment.
| Published by | Universitas Airlangga |
| Journal Name | Folia Medica Indonesiana |
| Contact Phone | - |
| Contact Name | - |
| Contact Email | - |
| Location | Kota surabaya, Jawa timur INDONESIA |
| Website | FMI| https://e-journal.unair.ac.id/index.php/FMI| |
| ISSN | ISSN : 23558393, EISSN : 2599056X, DOI : -, |
| Core Subject | Education, |
| Meta Subject | Other, |
| Meta Desc | Folia Medica Indonesiana publishes articles in the field of medical science in particular and health sciences in general, as well as a variety of other fields related to those two disciplines. Most of the articles are research article, and others are articles on case reports and literature review. In their presentation in the journal, the articles have passed meticulous editing process by the editors and review process and by competent peer reviewers, with national and international reputation, making the articles presented in this journal qualified, updated, and informative. |
| Penulis | Trengginas, Ganesha T , Hasmono, Didik , Subagyo, Roni |
| Publisher Article | Faculty of Medicine, Universitas Airlangga |
| Subtitle Article | Folia Medica Indonesiana Vol 54, No 4 (2018): December |
| Scholar Google | http://scholar.google.com/scholar?q=%2Bintitle%3A&… |
| View Article | https://e-journal.unair.ac.id/… |
| DOI | https://doi.org/10.20473/fmi.v54i4.… |
| DOI Number | DOI: 10.20473/fmi.v54i4.10704 |
| Download Article [1] | https://e-journal.unair.ac.id/FMI/articl… |
| Download Article [2] | http://download.garuda.ristekdikti.go.id… |
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