Objectives: To determine the effect of bone marrow mesenchy-mal stem cells (BMSCs) on BMP-15 expression and Graafian follicle count in endometriosis mice.Material and Methods: This study was a laboratory randomized clinical trial on Mus musculus. The object of the study was 42 mice which were divided into 3 groups, the control, endome-triosis, and endometriosis + BMSCs groups. Comparison of BMP-15 expression and Graafian follicle count between groups was evaluated.Results: Immunohistochemical analysis showed that BMP-15 expression in control, endometriosis, and endometriosis + BMSCs groups had p=0.551, p=0.446 and p=0.917 with ANOVA test p=0.273, indicating no statistically significant differences between groups . Graafian follicular count in the three groups had p=0.31, p=0.001, and p=0.006, with the Kruskal-Wallis test p=0.001. Graafian follicles in the endometriosis + BMSCs group were higher than those in control and endometriosis groups.Conclusion:In the endometriosis mouse model with bone mar-row stem cell transplantation the BMP-15 expression in each group did not show a difference, but a significant difference was found in the number of Graafian follicles.
| Published by | Universitas Airlangga |
| Journal Name | Majalah Obstetri dan Ginekologi |
| Contact Phone | - |
| Contact Name | - |
| Contact Email | - |
| Location | Kota surabaya, Jawa timur INDONESIA |
| Website | MOG| https://e-journal.unair.ac.id/index.php/MOG| |
| ISSN | ISSN : 08540381, EISSN : 25981013, DOI : 10.20473/mog.V27I32019.90-93, |
| Core Subject | Health, |
| Meta Subject | Health Professions, Medicine & Pharmacology, |
| Meta Desc | Majalah Obstetri & Ginekologi (MOG) or the Journal of Obstetrics & Gynecology Science is a scientific journal published by the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, in collaboration with the Indonesian Obstetrics and Gynecology Association (POGI) of Surabaya branch. |
| Penulis | Parasti, Ratriana Via , Widjiati, Widjiati , Dwiningsih, Sri Ratna |
| Publisher Article | Department of Obstetrics and Gynecology, Faculty of Medicine, Airlangga University |
| Subtitle Article | Majalah Obstetri & Ginekologi Vol 26, No 3 (2018): December |
| Scholar Google | http://scholar.google.com/scholar?q=%2Bintitle%3A&… |
| View Article | https://e-journal.unair.ac.id/… |
| DOI | https://doi.org/10.20473/mog.V26I32… |
| DOI Number | DOI: 10.20473/mog.V26I32018.107-111 |
| Download Article [1] | https://e-journal.unair.ac.id/MOG/articl… |
| Download Article [2] | http://download.garuda.ristekdikti.go.id… |
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