ABSTRACTBackground. Depression is a risk factor for diabetes and diabetes increase the risk for depression. Depression contributes to progression of diabetes mellitus. Examination of fructosamine is used to monitor blood sugar control for 2-3 weeks (according to age albumin). LPD evoke the relaxation response, which expected to improve symptoms of stress or depression.Objective. To determine the decrease in fructosamine levels in the group of patients with diabetes mellitus with depression symptoms after administration of fluoxetine alone compared with a combination of fluoxetine and LPD.Methods. This research conducted in Dr.Soeradji Tirtonegoro General Hospital, in May to August 2014. Distribution of data tested using the Shapiro-Wilk test. The differences between fructosamine and BDI (Beck Depression Inventory) before and after treatment tested with a pair t-test if normally distributed or Wilcoxon test if it was not normally distributed. The decrease in fructosamine and BDI both groups compared by independent t-test if normally distributed or Mann Whitney U test if not normally distributed. Differences were considered significant if p <0.05 with a confidence interval of 95%.Result. There was a significant decrease in fructosamine levels in treatment group from 293.90±140.042 to 239.01±133.13 after treatment with p value 0.017 (p <0.05). Control group from 263.13±163.65 to 219.01±149.33 with p value 0.001 (p<0.05). The decrease of fructosamine levels not differ in the treatment group 67.24±102.71 than the control group 71.14 ± 72.77 with p value = 0.902 (p> 0.05).Conclusion. LPD had no effect on fructosamine levels of type 2 diabetes mellitus patients with depression symptoms.Keywords: LPD, symptoms of depression, fructosamine, BDI (Beck Depression Inventory)

Published by Universitas Gadjah Mada
Journal Name Jurnal Acta Interna
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Location Kab. sleman, Daerah istimewa yogyakarta INDONESIA
Website jain| https://journal.ugm.ac.id/index.php/jain|
ISSN ISSN : 2303131X, EISSN : 25415441, DOI : -,
Core Subject Health,
Meta Subject Health Professions, Medicine & Pharmacology,
Meta DescThe Journal considers any original research that advocates change in, or illuminates, clinical practice. The journal also publishes interesting and informative reviews and opinions pieces on any topics connected with clinical practice. Manuscripts must be solely the work of the author(s) stated, not have been published previously elsewhere, and not be under consideration by another journal. all papers should be written to be clearly understandable to the journal`s readers in a wide range of specialities and countries. Diagrams, figures, and photographs should be used to supplement and enhance the text.
PenulisMuin, Natsir , Siswanto, Agus , Asdie, Ahmad Husain
Publisher ArticleFaculty of Medicine Universitas Gadjah Mada
Subtitle Article Acta Interna The Journal of Internal Medicine Vol 7, No 1 (2017): Acta Interna The Journal of Internal Medicine
Scholar Googlehttp://scholar.google.com/scholar?q=%2Bintitle%3A&…
View Articlehttps://journal.ugm.ac.id/jain…
DOIhttps://doi.org/10.22146/actaintern…
DOI Number DOI: 10.22146/actainterna.48402
Download Article [1] https://journal.ugm.ac.id/jain/article/d…
Download Article [2] http://download.garuda.ristekdikti.go.id…

 

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