Bone graft use in maxillofacial surgery is currently developing, though some problems still persist. One of promising solutions to the problems is application of platelet rich plasma which may accelerate soft tissue healing and bone formation. This study aims to provide basic understanding to the development of PRP application in bone healing where bone graft is applied on human maxillae. Bone defects were made on maxillae of albino rabbits, with an application of bone graft in control group and bone graft plus PRP in treatment group. Histopathological analysis was performed in both groups to assess osteoblast density and collagen tissue area. On day 21st, more osteoblast density and collagen area in treatment group are significantly observed (p<0.05, 95% confidence interval). Observations were made on hard callus formation. In conclusions, platelet rich plasma may increase density of osteoblast in rabbit maxillary bone graft.

Published by Universitas Airlangga
Journal Name Folia Medica Indonesiana
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Location Kota surabaya, Jawa timur INDONESIA
Website FMI| https://e-journal.unair.ac.id/index.php/FMI|
ISSN ISSN : 23558393, EISSN : 2599056X, DOI : -,
Core Subject Education,
Meta Subject Other,
Meta DescFolia Medica Indonesiana publishes articles in the field of medical science in particular and health sciences in general, as well as a variety of other fields related to those two disciplines. Most of the articles are research article, and others are articles on case reports and literature review. In their presentation in the journal, the articles have passed meticulous editing process by the editors and review process and by competent peer reviewers, with national and international reputation, making the articles presented in this journal qualified, updated, and informative.
PenulisSaputro, Iswinarno Doso , Hutagalung, Magda Rosalina , Wahdini, Siti Isya
Publisher ArticleFaculty of Medicine, Universitas Airlangga
Subtitle Article Folia Medica Indonesiana Vol 53, No 1 (2017): JANUARY - MARCH 2017
Scholar Googlehttp://scholar.google.com/scholar?q=%2Bintitle%3A&…
View Articlehttp://e-journal.unair.ac.id/F…
DOIhttps://doi.org/10.20473/fmi.v53i1.…
DOI Number DOI: 10.20473/fmi.v53i1.5485
Download Article [1] http://e-journal.unair.ac.id/FMI/article…
Download Article [2] http://download.garuda.ristekdikti.go.id…

 

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