The purpose of this study was to determine the effects of DLBS1033 on blood pressure reduction in hypertension--induced wistar strain rats. Design used in this study was true experimental design. The study was conducted at Biomedical Laboratory, Physiology, Faculty of Dentistry, Jember University, and Clinical and Community Pharmacy Laboratory, Pharmacy Faculty, Jember University. Subjects were taken from male Wistar rats aged 2-3 months, weighing 150-200 grams, as many as 22 rats. Intervention samples were induced into hypertension by giving prednisone in a dose of 1.5 mg/kg/day orally and 2% NaCl followed DLBS1033 of 0.5 grams/kgbw/day orally in the treatment group. T test results on systolic blood pressure (p = 0.00), which was <0.05, showing significant differences in systolic blood pressure in treatment groups. It can be concluded that DLBS1033 can lower systolic blood pressure in wistar rats with induced hypertension using prednisone 1.5 mg/kgbw/day and NaCl 2%.
| Published by | Universitas Airlangga |
| Journal Name | Folia Medica Indonesiana |
| Contact Phone | - |
| Contact Name | - |
| Contact Email | - |
| Location | Kota surabaya, Jawa timur INDONESIA |
| Website | FMI| https://e-journal.unair.ac.id/index.php/FMI| |
| ISSN | ISSN : 23558393, EISSN : 2599056X, DOI : -, |
| Core Subject | Education, |
| Meta Subject | Other, |
| Meta Desc | Folia Medica Indonesiana publishes articles in the field of medical science in particular and health sciences in general, as well as a variety of other fields related to those two disciplines. Most of the articles are research article, and others are articles on case reports and literature review. In their presentation in the journal, the articles have passed meticulous editing process by the editors and review process and by competent peer reviewers, with national and international reputation, making the articles presented in this journal qualified, updated, and informative. |
| Penulis | Suryono, Suryono |
| Publisher Article | Faculty of Medicine, Universitas Airlangga |
| Subtitle Article | Folia Medica Indonesiana Vol 51, No 3 (2015): July - September 2015 |
| Scholar Google | http://scholar.google.com/scholar?q=%2Bintitle%3A&… |
| View Article | http://e-journal.unair.ac.id/F… |
| DOI | https://doi.org/10.20473/fmi.v51i3.… |
| DOI Number | DOI: 10.20473/fmi.v51i3.2829 |
| Download Article [1] | http://e-journal.unair.ac.id/FMI/article… |
| Download Article [2] | http://download.garuda.ristekdikti.go.id… |