Thaspiviridae

Nitmarvirus
	TEM image of virions of Nitrosopumilus spindle-shaped virus 1 (Nitmarvirus NSV1).
Virus classification
(unranked):	Virus
Family:	Thaspiviridae
Genus:	Nitmarvirus
Species
	Nitmarvirus NSV1;
Synonyms
	Nitmarvirus NSV1 Nitrosopumilus spindle-shaped virus 1 Virus name; NSV1 Virus name abbr.; MK57005: GenBank accession; NC_048199 REFSEQ accession;

Thaspiviridae is a family of incertae sedis spindle-shaped viruses. The family contains a single genus, Nitmarvirus, which contains a single species, Nitmarvirus NSV1.^[1]

Thaspiviridae are known to infect mesophilic ammonia-oxidizing archaea of the genus Nitrosopumilus.^[2]

Structure

The virion is spindle-shaped, measuring 64±3 nm in diameter and 112±6 nm in length, with short fibres at one pole. Its morphology is very similar to that of the members of the families Fuselloviridae and Halspiviridae, which infect hyperthermophilic and hyperhalophilic archaea, respectively.^[2]

Genome

Its genome is linear dsDNA of length 27–29 kbp, with 176 bp terminal inverted repeats. The virus genome is predicted to carry 48 genes. With the exception of protein-primed B DNA polymerase, which is also found in several groups of archaeal viruses and non-viral mobile genetic elements that also have linear genomes with terminal inverted repeats, the proteins encoded by Nitrosopumilus spindle-shaped virus 1 are unrelated to those of other archaeal and bacterial viruses.^[2]

Replication

The virus is non-lytic (capable of exiting host cells without killing them), and chronic (can be demonstrated in the body at all times and the disease may be present or absent for an extended period of time). The virus genome is likely to be replicated by the virus-encoded protein-primed family B DNA polymerase, as has been inferred for other viruses. The virus also encodes a proliferating cell nuclear antigen which is also likely to be involved in viral genome replication.^[2]

References

^ "Virus Taxonomy: 2022 Release". International Committee on Taxonomy of Viruses (ICTV). March 2023. Retrieved 19 August 2023.
^ ^a ^b ^c ^d Kim, JG; Gazi, KS; Krupovic, M; Rhee, SK; Ictv Report, Consortium (July 2021). "ICTV Virus Taxonomy Profile: Thaspiviridae 2021". The Journal of General Virology. 102 (7): 001631. doi:10.1099/jgv.0.001631. PMC 8491892. PMID 34328827.