Seadornavirus

Seadornavirus
Electron micrograph of Banna virus
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Duplornaviricota
Class: Resentoviricetes
Order: Reovirales
Family: Sedoreoviridae
Subfamily: Sedoreovirinae
Genus: Seadornavirus

Seadornavirus is a genus of viruses, in the family Reoviridae, in the subfamily Sedoreovirinae. Human, cattle, pig, and mosquitoes serve as natural hosts.[1][2] There are three species in this genus: Banna virus (BAV), Kadipiro virus and Liao ning virus. Each of these viruses has been isolated from Aedes, Anopheles and Culex mosquito populations, but only BAV has been shown to cause infection in humans, in which the symptoms are similar to Japanese encephalitis—fever, malaise and encephalitis.[3] The word seadornavirus is an portmanteau, meaning Southeast Asian dodeca RNA virus.

Taxonomy

The following three species are assigned to the genus:[2]

Structure

Viruses in Seadornavirus are non-enveloped, with icosahedral geometries, and T=13, T=2 symmetry. The diameter is around 60-70 nm. Genomes are linear and segmented. Segments range in length from 862 to 3747 base pairs, totaling 21 kb in length. The genome codes for 12 proteins.[1]

Genus Structure Symmetry Capsid Genomic arrangement Genomic segmentation
Seadornavirus Icosahedral T=13, T=2 Non-enveloped Linear Segmented

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment to host receptors, which mediates endocytosis. Replication follows the double-stranded RNA virus replication model. Double-stranded RNA virus transcription is the method of transcription. The virus exits the host cell by monopartite non-tubule guided viral movement. Human, cattle, pig, mosquitoes (arthropod-borne), and mosquitoes serve as the natural host. Transmission routes are zoonosis and bite.[1]

Genus Host details Tissue tropism Entry details Release details Replication site Assembly site Transmission
Seadornavirus Humans; cows; pigs; mosquitoes None Cell receptor endocytosis Cell death Cytoplasm Cytoplasm Zoonosis; arthropod bite

References

  1. ^ a b c "Viral Zone". ExPASy. Retrieved 15 June 2015.
  2. ^ a b ICTV. "Virus Taxonomy: 2014 Release". Retrieved 15 June 2015.
  3. ^ Attoui H, Mohd Jaafar F, de Lamballerie X, Mertens PPC Seadornavirus, Reoviridae In: Fauquet CM, Mayo MA, Maniloff J, Desselberger U, Ball LA, editors. Virus taxonomy: eighth report of the international committee on taxonomy of viruses. London: Elsevier/Academic Press; 2005. p. 504–10