Sappinia diploidea is a free-living[1]amoeba species.[2]
Background
Sappinia can be found worldwide. It usually occurs in elk and buffalo feces, places where farm animals are known to eat, soil containing rotting plants, and fresh water sources.[2]
Clinical significance
It is capable of causing infectious disease in humans.[3][4][5]
Symptoms of Sappinia infection
Symptoms of a Sappinia infection include headache, photophobia, nausea or upset stomach, vomiting, blurred vision, and loss of consciousness.
A scan of the one, infected patient’s brain also revealed a 2-centimeter tumor-like mass on the back left section of his brain.[2]
Treatment
Treatment for the one identified case of Sappinia infection included the removal of a tumor in the brain and a series of drugs given to the patient after surgery. This treatment led to the patient’s full recovery.[6][7][8]
^Wylezich, C.; Walochnik, J.; Michel, R. (2009). "High genetic diversity of Sappinia-like strains (Amoebozoa, Thecamoebidae) revealed by SSU rRNA investigations". Parasitology Research. 105 (3): 869–873. doi:10.1007/s00436-009-1482-1. PMID19495795. S2CID28942657.
^Gelman, B.B. "Parasites-Sappinia". Amoebic encephalitis due to Sappinia diploidea. JAMA, 2001. Retrieved 8 December 2011.
^Gelman BB, Popov V, Chaljub G, et al. (October 2003). "Neuropathological and ultrastructural features of amebic encephalitis caused by Sappinia diploidea". J. Neuropathol. Exp. Neurol. 62 (10): 990–8. doi:10.1093/jnen/62.10.990. PMID14575235.
^Marciano‐Cabral F (2009). "Free‐Living Amoebae as Agents of Human Infection". J Infect Dis. 199 (8): 1104–1106. doi:10.1086/597474. PMID19302009.