Lysosomal trafficking regulator

lysosomal trafficking regulator
Identifiers
Symbol	LYST
Alt. symbols	CHS1
NCBI gene	1130
HGNC	1968
OMIM	606897
RefSeq	NM_000081
UniProt	Q99698
Other data
Locus	Chr. 1 q42.1-42.2
Search for Structures Swiss-model Domains InterPro

Lysosomal trafficking regulator is a vesicular transport protein associated with Chédiak–Higashi syndrome.

In melanocytic cells LYST gene expression may be regulated by MITF.[1]

References

1. Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971.

External links

• GeneReviews/NCBI/NIH/UW entry on Chediak-Higashi Syndrome
• lysosomal+trafficking+regulator+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)