Itramin tosilate

Itramin tosilate

Clinical data
Trade names	Nilatil
Other names	Itramin tosylate
ATC code	C01DX01 (WHO)
Identifiers
IUPAC name 2-aminoethyl nitrate; 4-methylbenzenesulfonic acid
CAS Number	13445-63-1^Y
PubChem CID	26000
DrugBank	DBSALT002523
ChemSpider	24219
UNII	W9H0R50KY0
KEGG	D07157
ChEBI	CHEBI:136001
ChEMBL	ChEMBL2106780
CompTox Dashboard (EPA)	DTXSID30158705
Chemical and physical data
Formula	C9H14N2O6S
Molar mass	278.28 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.C(CO[N+](=O)[O-])N
InChI InChI=1S/C7H8O3S.C2H6N2O3/c1-6-2-4-7(5-3-6)11(8,9)10;3-1-2-7-4(5)6/h2-5H,1H3,(H,8,9,10);1-3H2 Key:HPPBBWMYZVALRK-UHFFFAOYSA-N

Itramin tosilate (INN), or itramin tosylate (more commonly), is a vasodilator.[1][2][3][4][5][6]

References

1. Batterman RC, Mouratoff GJ (June 1963). "Anginal syndrome. Treatment with a long-acting nitrate (itramin tosylate)". California Medicine. 98 (6): 318–9. PMC 1575756. PMID 13966844.
2. McGrath JC (June 2013). "2-Aminoethylnitrate: Earlier investigation as a drug was missed by recent authors due to changes in nomenclature". British Journal of Pharmacology. 169 (4): 949–50. doi:10.1111/bph.12148. PMC 3687673. PMID 23711023.
3. Ehrenberger W (August 1960). "[On the effects of 2-aminoethylnitrate p-toluenesulfonate (Nilatil) on coronary circulation disorders]". Wiener Zeitschrift für Innere Medizin und Ihre Grenzgebiete. 41: 323–4. PMID 13725976.
4. Fremont RE (May 1967). "Clinical and cardiographic evaluation of a new nitrate, itramin tosylate". Current Therapeutic Research, Clinical and Experimental. 9 (5): 235–46. PMID 4963057.
5. Kinnard WJ, Vogin EE, Aceto MD, Buckley JP (July 1964). "The Coronary Vasodilatory Effects of 2-Aminoethlynitrate p-Toluenesulfonate". Angiology. 15 (7): 312–5. doi:10.1177/000331976401500703. PMID 14177999. S2CID 29870356.
6. Takenaka F, Umeda T (July 1976). "Effects of propranolo, itramin tosylate and dipyridamole on myocardial phosphate metabolism in anoxic perfused rat hearts". Archives Internationales de Pharmacodynamie et de Therapie. 222 (1): 45–54. PMID 10860.