It has an oceanic climate, with mild to warm summers, and mild to cool winters. Temperatures rarely fall below 10 °C in winter and rarely climb beyond 28 °C in summer. Rain occurs year-round, with a slight peak in the spring months, brought by the humid sea-winds from the Indian Ocean rising and releasing their precipitation along the Langeberg, Outeniqua and Tsitsikamma Mountains just inland of the coast. The Garden Route is closely linked with the Origin of Human Culture, due to archaeological finds in the Plettenberg Bay, Mossel Bay and Stilbaai areas.
The Route is sandwiched between the aforementioned mountains and the Indian Ocean, with mountain passes, including the Outeniqua Pass and Garcia's Pass, linking the area with the arid Little Karoo. The Outeniqua, Grootvadersbosch and Tsitsikamma indigenous forests are a unique mixture of Cape Fynbos and Temperate Forest and offer hiking trails and eco-tourism activities. Nearly 300 species of birdlife are to be found in a variety of habitats ranging from fynbos to forest to wetlands.