Copiparvovirus is a genus of viruses in subfamily Parvovirinae of the virus family Parvoviridae.[1][2] Pigs and cows are known to serve as natural hosts. There are seven species in this genus.[3][4][5]
Taxonomy
The following seven species are assigned to the genus:[5]
Viruses in genus Copiparvovirus are non-enveloped, with icosahedral and round geometries, and T=1 symmetry. The diameter is around 18-26 nm. Genomes are linear, around 6kb in length.[2][4]
Genus
Structure
Symmetry
Capsid
Genomic arrangement
Genomic segmentation
Copiparvovirus
Icosahedral
T=1
Non-enveloped
Linear
None
Life cycle
Viral replication is nuclear. Entry into the host cell is achieved by attachment to host receptors, which mediates clathrin-mediated endocytosis. Replication follows the rolling-hairpin model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear pore export. Bovine serve as the natural host.[4]
Genus
Host details
Tissue tropism
Entry details
Release details
Replication site
Assembly site
Transmission
Copiparvovirus
Ungulates
Not defined
Clathrin-mediated endocytosis
Lysis
Nucleus
Nucleus
Unknown
References
^Cotmore, SF; Agbandje-McKenna, M; Canuti, M; Chiorini, JA; Eis-Hubinger, A; Hughes, J; Mietzsch, M; Modha, S; Ogliastro, M; Pénzes, JJ; Pintel, DJ; Qiu, J; Soderlund-Venermo, M; Tattersall, P; Tijssen, P; and the ICTV Report Consortium (2019). "ICTV Virus Taxonomy Profile: Parvoviridae". Journal of General Virology. 100 (3): 367–368. doi:10.1099/jgv.0.001212. PMC6537627. PMID30672729.