In addition to his fame in religious sciences and Tasawwuf, Akshemsaddin was popular in the fields of medicine and pharmacology. There is not much reference to how he acquired this knowledge, but the OrientalistElias John Wilkinson Gibb notes in his work History of Ottoman Poetry that Akshamsaddin learned from Haji Bayram Wali during his years with him.[7] Akshamsaddin was also knowledgeable in the treatment of psychological and spiritual disorders.[8][9][10][11][12] Akshamsaddin mentioned the microbe in his work Maddat ul-Hayat (The Material of Life) about two centuries prior to Antonie van Leeuwenhoek's discovery through experimentation:
It is incorrect to assume that diseases appear one by one in humans. Disease infects by spreading from one person to another. This infection occurs through seeds that are so small they cannot be seen but are alive.[13][14]
Different sources claim that Akshemsaddin had seven or twelve sons; the youngest was the noted poet Ḥamd Allāh Ḥamdī.[15]
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