The 2015–16 Puebla F.C. season was the club's 69th professional season in Mexico's top-flight football league. The season is split into two tournaments—the Torneo Apertura and the Torneo Clausura—each with identical formats and each contested by the same eighteen teams. The club also played Supercopa MX and Copa Libertadores.
First-team squad
Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply. Players may hold more than one non-FIFA nationality.
After Santos laguna reached the Clausura 2015 final, Puebla earned a passed to the Copa Libertadores 2016 due to Santos pass to the 2016 Concachampions Cup.[5] On December 22, 2015 the Conmebol will have the lottery in Paraguay in order to define Puebla's rival. Due to fellow Mexican club Tigres who is the 2015 Runner up, Puebla won the right to home advantage in the series that will award 1st stage participation .