The 2000 Kilkenny Senior Hurling Championship was the 106th staging of the Kilkenny Senior Hurling Championship since its establishment by the Kilkenny County Board in 1887. The championship began on 19 August 2000 and ended on 22 October 2000.
On 15 October 2000, Graigue-Ballycallan won the title after a 0–16 to 0–09 defeat of O'Loughlin Gaels in the final at Nowlan Park.[2] It was their second championship title overall and their first title in two championship seasons. It remains their last championship triumph.
Nigel Skehan of the O'Loughlin Gaels club was the championship's top scorer with 2-23.