诺孕烯酮 商品名 Ogyline, Planor, Miniplanor 其他名稱 RU-2010; A-301; 17α-Ethynyltrienolone; 17α-Ethynyltrenbolone; Δ9,11 -Norethisterone; 17α-Ethynylestra-4,9,11-trien-17β-ol-3-one 给药途径 口服给药 藥物類別 Progestogen ; Progestin ; Androgen ; Anabolic steroid ATC碼
(8S ,13S ,14S ,17R )-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a ]phenanthren-3-one
CAS号 848-21-5 Y PubChem CID ChemSpider UNII KEGG CompTox Dashboard (EPA ) ECHA InfoCard 100.011.544 化学式 C 20 H 22 O 2 摩尔质量 294.39 g·mol−1 3D模型(JSmol )
O=C4\C=C3/C(=C2/C=C\[C@]1([C@@H](CC[C@]1(C#C)O)[C@@H]2CC3)C)CC4
InChI=1S/C20H22O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,8,10,12,17-18,22H,4-7,9,11H2,2H3/t17-,18+,19+,20+/m1/s1
Y Key:GVDMJXQHPUYPHP-FYQPLNBISA-N
Y
诺孕烯酮 (英語:Norgestrienone ,或译为去甲孕三烯酮 ,商品名 : Ogyline , Planor , Miniplanor 等)是一种甾体 药物 ,分子式C20 H22 O2 ,由法国药企Roussel Uclaf 开发,可用作复合口服避孕药 ,常与炔雌醇 联用[ 1] [ 2] [ 3] [ 4] [ 5] 。
参考文献
^ Elks J. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies . Springer. 14 November 2014: 887–. ISBN 978-1-4757-2085-3 .
^ Morton IK, Hall JM. Concise Dictionary of Pharmacological Agents: Properties and Synonyms . Springer Science & Business Media. 6 December 2012: 202– [2023-02-02 ] . ISBN 978-94-011-4439-1 . (原始内容存档 于2023-01-10).
^ Diaz S, Pavez M, Quinteros E, Diaz J, Robertson DN, Croxatto HB. Clinical trial with subdermal implants containing norgestrienone. Contraception. October 1978, 18 (4): 429–40. PMID 720075 . doi:10.1016/0010-7824(78)90027-6 .
^ Index Nominum 2000: International Drug Directory . Taylor & Francis. January 2000: 751–. ISBN 978-3-88763-075-1 .
^ Sweetman, Sean C. (编). Sex hormones and their modulators . Martindale: The Complete Drug Reference 36th. London: Pharmaceutical Press. 2009: 2122 [2023-02-02 ] . ISBN 978-0-85369-840-1 . (原始内容存档 于2020-05-29). Norgestrienone is a progestogen structurally related to norethisterone that has been used as an oral contraceptive. Typical doses have been 2 mg daily with an oestrogen, and 350 micrograms daily when used alone.