芫花素

芫花素
Skeletal formula of genkwanin
Ball-and-stick model of genkwanin
IUPAC名
5-hydroxy-2-(4-hydroxyphenyl)-7-methoxychromen-4-one
别名 Gengkwanin
Apigenin 7-methyl ether
4',5-Dihydroxy-7-methoxyflavone
4',5-dihydroxy-7-methoxy flavone
5,4'-Dihydroxy-7-methoxyflavone
识别
CAS号 437-64-9  checkY=
PubChem 5281617
ChemSpider 4444936
SMILES
 
  • COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)O)O
InChI
 
  • 1/C16H12O5/c1-20-11-6-12(18)16-13(19)8-14(21-15(16)7-11)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3
InChIKey JPMYFOBNRRGFNO-UHFFFAOYAO
性质
化学式 C16H12O5
摩尔质量 284.27 g/mol g·mol⁻¹
若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

芫花素（英语：Genkwanin）是一种芹菜素衍生的O-甲基化黄酮，为许多抗炎活性的草药中主要活性成分[1]。提取自瑞香料植物芫花中，也存在于普通赤杨的种子等[2]。

参考资料

  1. ^ Gao Yuan; Fen Liu, Lei Fang, Runlan Cai, Chuanjie Zong, and Yun Qi. Genkwanin inhibits proinflammatory mediators mainly through the regulation of miR-101/MKP-1/MAPK pathway in LPS-activated macrophages. PloS one. 2014, 9 (5): e96741. 
  2. ^ O'Rourke, Ciara; Byres, Maureen; Delazar, Abbas; Kumarasamy, Yashodharan; Nahar, Lutfun; Stewart, Fiona; Sarker, Satyajit D. Hirsutanonol, oregonin and genkwanin from the seeds of Alnus glutinosa (Betulaceae). Biochemical Systematics and Ecology. 2005, 33 (7): 749–752 [2017-08-11]. doi:10.1016/j.bse.2004.10.005. （原始内容存档于2012-08-23）.