The aim of this study to know the effect of job stress, job pressure and job fatigue on employee performance at BNK BRI of Muara Bulian Are. Data collecting used survey method, that is to obtain information from respondents by using interview techniques and spreading the list of questions and to measureit by using Likert scale. Population of the research is employees at BANK BRI of Muara Bulian Area. Analyzer used is multiple linear regression, this method using computer assistance through program SPSS 20.0 for windows. From the calculation of SPSS 20.0, it found that is the job stress variable is 2,193, because tcount> from ttable, (2,193> 1.68195 hence Ho accepted and Ha rejected, it means that independent variable has influence to dependent variable, which means there is partial influence between job stress to employees performance at Bank BRI of MuaraBulian Area.Variable job pressure of 0.254, Because tcount