The purpose of this study was to assess the effectiveness of integrated local wisdom sheets for local wisdom on students' critical thinking skills. This type of pre-experimental research with the design of one groups pre-test post-test design. Samples were 18 students taken with saturated sampling technique. The instrument used was the Critical Thinking Skills Test (TKBK) with indicators: 1) interpretation; 2) analysis; 3) conclusions; 4) evaluations; 5) explanations; and 6) self-regulation. Data were analyzed descriptively and in paired sample test statistics. The results showed that the integrated inquiry wisdom local worksheet was declared effective based on the results of the N-Gain analysis with an average value of 0.65 (moderate). Indicators of interpretation and evaluation reached a percentage of 81 with a category (very high). Skills indicators explain 80 in categories (high), analysis indicators and skills conclude 60 categories (low), and the lowest percentage in self-regulation indicators reaches 37 in categories (very low). Weak skills in analyzing and making conclusions, because student self-regulation skills are low. This condition demands the need to improve self-regulation by developing cognitive monitoring through an emphasis on learning that can practice scientific curiosity skills.