DESCRIPTION OF FAECAL CULTURE RESULTS IN DIARRHEA PATIENT DUE TO ANTIBIOTIC USE  1Suci Tresna, IGAA Putri Sri Rejeki1 Puspa Wardhani1   1Clinical Pathology Spesialization Programme, Department of Clinical Pathology Faculty of Medicine Airlangga University-DR Soetomo Hospital Surabaya 2Department of Clinical Pathology, Faculty of Medicine Airlangga UniversityDr. Soetomo Hospital, Surabaya   ABSTRACT  Background : Diarrhea infection is common in developing countries and causes death of around 3 million people every year. Diarrhea is also the second leading cause of death in infants. Riskesdas in 2013 showed 30,775 cases of diarrhea. Causes such as bacterial infections Salmonella, shigella, Vibrio, Entamoeba and Yersinia. Other influences can occur due to viral and fungal infections. Diarrhea is a nosocomial infection that is common in hospitalized patients due to long-term use of antibiotics caused by Clostridium difficile. This study was a follow-up study of diarrhea patients who received antibiotic therapy for more than 2 days with the results of C.difficile negative toxin, then continued with faecal culture examination. This study aims is to look the description causes of diarrhea other than c.difficile in patients that receiving long-term antibiotic therapyMethods: This research is experimental descriptive. Samples were taken from 30 diarrhea patients with 2 x 24 hours of antibiotic use who were hospitalized in the ICU, Dr. Soetomo Hospital Surabaya from August 2017-May 2018. Samples with negative C.difficile toxin results are then followed by faecal culture examination using conventional methods.Results: The results of culture examination from  30 samples there were 3 samples with positive culture results ESBL, 25 other samples showed negative culture results.Conclusion: The results of faecal culture examination showed a description causes of the diarrhea in patients that receiving antibiotic therapy is pathogenic E.coli (ESBL). The possibility of other causes that cannot be detected from the culture such as viral and fungal infections still requires further research.