Trypanosoma equiperdum

Trypanosoma equiperdum
Scientific classification Edit this classification
Domain: Eukaryota
Phylum: Euglenozoa
Class: Kinetoplastea
Order: Trypanosomatida
Family: Trypanosomatidae
Genus: Trypanosoma
Species:
T. equiperdum
Binomial name
Trypanosoma equiperdum
Døflein, 1901

Τrypanosoma equiperdum is a species of kinetoplastid parasites that causes Dourine or covering sickness in horses and other animals in the family equidae. T. equiperdum is the only known trypanosome that is not spread by an insect vector.[1] There has been substantial controversy surrounding whether T. equiperdum should be considered a unique species, or a strain of T. evansi or T. brucei.[1][2] T. equiperdum is unique in that its kinetoplast, the network of connected rings that make up its mitochondrial DNA, consists of thousands of "minicircles" that are identical in sequence.[3]

References

  1. ^ a b Claes F, Buscher P, Touratier L, Goddeeris BM (2005). "Trypanosoma equiperdum: master of disguise or historical mistake?". Trends in Parasitology. 21 (7): 316–321. doi:10.1016/j.pt.2005.05.010. PMID 15923142.
  2. ^ Lai, D.; Hashimi, Lun; Ayala, Lukes (2008). "Adaptations of Trypanosoma brucei to gradual loss of kinetoplast DNA: Trypanosoma equiperdum and Trypanosoma evansi are petite mutants of T. brucei". Proc Natl Acad Sci USA. 105 (6): 1999–2004. Bibcode:2008PNAS..105.1999L. doi:10.1073/pnas.0711799105. PMC 2538871. PMID 18245376.
  3. ^ Shapiro, Theresa (1993). "Kinetoplast DNA maxicircles: networks within networks". Proceedings of the National Academy of Sciences. 90 (16): 7809–7813. Bibcode:1993PNAS...90.7809S. doi:10.1073/pnas.90.16.7809. PMC 47232. PMID 8395055.


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