Lamositele made his professional debut on March 22, 2015, playing 9 minutes off the bench for Saracens in an LV= Cup loss to Exeter Chiefs.[2] He helped Saracens win the European Champions Cup in 2017 and 2019, featuring in both finals.[3][4]
On 20 February 2020, Lamositele signed for French giants Montpellier in the Top 14 ahead of the 2020–21 season.[5]
On 15 May 2024, Lamositele signed for Premiership club Harlequins ahead of the 2024-25 season.[6]
International career
Lamositele debuted for the U.S. in 2013. Lamositele scored his first try for the United States in the 2015 Pacific Nations Cup against Samoa.[7] Lamositele played for the U.S. at the 2015 and 2019 Rugby World Cups.