She was a daughter of general Tống Phước Khuông of the Nguyễn lords. Nguyễn Ánh married her when he was 18. Empress Thừa Thiên had two sons with Gia Long: Nguyen Phuc Chieu (who died after several days) and Crown Prince Nguyễn Phúc Cảnh. After her death, she was buried at Gia Long's Thiên Thọ tomb, alongside the Emperor.
References
Tôn Thất Bình (1997). Kể chuyện chín Chúa mười ba Vua triều Nguyễn (in Vietnamese). Da Nang: Đà Nẵng Publishing House. pp. 45–47.