Bioinformatician
Suzanna (Suzi) E. Lewis was a scientist and Principal investigator at the Berkeley Bioinformatics Open-source Project based at Lawrence Berkeley National Laboratory until her retirement in 2019. Lewis led the development of open standards and software for genome annotation and ontologies .[ 2] [ 3] [ 4]
Education
Lewis has Master of Science degrees in Biology and Computer science .[ 5]
Research
She led the team responsible for the systematic annotation[ 6] of the Drosophila melanogaster genome, which included development of the Gadfly[ 7] annotation pipeline and database framework, and the annotation curation tool Apollo.[ 8] Lewis' work in genome annotation also includes playing instrumental roles in the GASP[ 9] community assessment exercises to evaluate the state of the art in genome annotation, development of the Gbrowse[ 10] genome browser , and the data coordination center for the modENCODE project.[ 11] In addition to her work in genome annotation, Lewis has been a leader in the development of Open Biomedical Ontologies (OBO),[ 12] National Center for Biomedical Ontology (NCBO),[ 13] [ 14] contributing to the Gene Ontology [ 15] Sequence Ontology ,[ 16] Uberon anatomy ontologies,[ 17] and developing open software for editing and navigating ontologies such as AmiGO,[ 18] OBO-Edit[ 19] and Phenote.
Awards and honors
In 2005 Lewis was elected a fellow of the American Association for the Advancement of Science in recognition of her contributions to science in the fields of Information, Computing, and Communication.[ 1]
References
^ a b "AAAS News & Notes" . Archived from the original on 2013-03-18. Retrieved 16 June 2012 .
^ "Nominations for the Benjamin Franklin Award for Open Access in the Life Sciences 2012" . Archived from the original on 2013-01-12.
^ "Suzi Lewis - BioPerl" . Archived from the original on 2012-02-05.
^ "Berkeley Drosophila Genome Project BDGP: Contact Info" . Archived from the original on 2012-03-16.
^ "Suzanna Lewis: Berkeley Bioinformatics Open-source Projects (BBOP)" . Archived from the original on 2012-10-23.
^ Misra, S.; Crosby, M.; Mungall, C.; Matthews, B.; Campbell, K.; Hradecky, P.; Huang, Y.; Kaminker, J.; Millburn, G.; Prochnik, S. E.; Smith, C. D.; Tupy, J. L.; Whitfied, E. J.; Bayraktaroglu, L.; Berman, B. P.; Bettencourt, B. R.; Celniker, S. E.; De Grey, A. D.; Drysdale, R. A.; Harris, N. L.; Richter, J.; Russo, S.; Schroeder, A. J.; Shu, S. Q.; Stapleton, M.; Yamada, C.; Ashburner, M.; Gelbart, W. M.; Rubin, G. M.; Lewis, S. E. (2002). "Annotation of the Drosophila melanogaster euchromatic genome: A systematic review" . Genome Biology . 3 (12): research0083.research0081–83.research0081. doi :10.1186/gb-2002-3-12-research0083 . PMC 151185 . PMID 12537572 .
^ Mungall, C. J.; Misra, S.; Berman, B. P.; Carlson, J.; Frise, E.; Harris, N.; Marshall, B.; Shu, S.; Kaminker, J. S.; Prochnik, S. E.; Smith, C. D.; Smith, E.; Tupy, J. L.; Wiel, C.; Rubin, G. M.; Lewis, S. E. (2002). "An integrated computational pipeline and database to support whole-genome sequence annotation" . Genome Biology . 3 (12): research0081.research0081–81.research0081. doi :10.1186/gb-2002-3-12-research0081 . PMC 151183 . PMID 12537570 .
^ Lewis, S. E. ; Searle, S. M.; Harris, N.; Gibson, M.; Lyer, V.; Richter, J.; Wiel, C.; Bayraktaroglir, L.; Birney, E. ; Crosby, M. A.; Kaminker, J. S.; Matthews, B. B.; Prochnik, S. E.; Smithy, C. D.; Tupy, J. L.; Rubin, G. M.; Misra, S.; Mungall, C. J.; Clamp, M. E. (2002). "Apollo: A sequence annotation editor" . Genome Biology . 3 (12): research0082.research0081–82.research0081. doi :10.1186/gb-2002-3-12-research0082 . PMC 151184 . PMID 12537571 .
^ Reese, M. G.; Hartzell, G.; Harris, N. L.; Ohler, U.; Abril, J. F.; Lewis, S. E. (2000). "Genome annotation assessment in Drosophila melanogaster" . Genome Research . 10 (4): 483– 501. doi :10.1101/gr.10.4.483 . PMC 310877 . PMID 10779488 .
^ Stein, L. D. ; Mungall, C.; Shu, S.; Caudy, M.; Mangone, M.; Day, A.; Nickerson, E.; Stajich, J. E.; Harris, T. W.; Arva, A.; Lewis, S. (2002). "The Generic Genome Browser: A Building Block for a Model Organism System Database" . Genome Research . 12 (10): 1599– 1610. doi :10.1101/gr.403602 . PMC 187535 . PMID 12368253 .
^ Washington, N. L.; Stinson, E. O.; Perry, M. D.; Ruzanov, P.; Contrino, S.; Smith, R.; Zha, Z.; Lyne, R.; Carr, A.; Lloyd, P.; Kephart, E.; McKay, S. J.; Micklem, G.; Stein, L. D.; Lewis, S. E. (2011). "The modENCODE Data Coordination Center: Lessons in harvesting comprehensive experimental details" . Database . 2011 : bar023. doi :10.1093/database/bar023 . PMC 3170170 . PMID 21856757 .
^ Smith, B. ; Ashburner, M. ; Rosse, C.; Bard, J.; Bug, W.; Ceusters, W.; Goldberg, L. J.; Eilbeck, K.; Ireland, A.; Mungall, C. J.; Leontis, N.; Rocca-Serra, P.; Ruttenberg, A.; Sansone, S. A.; Scheuermann, R. H.; Shah, N.; Whetzel, P. L.; Lewis, S. (2007). "The OBO Foundry: Coordinated evolution of ontologies to support biomedical data integration" . Nature Biotechnology . 25 (11): 1251– 1255. doi :10.1038/nbt1346 . PMC 2814061 . PMID 17989687 .
^ Musen, M. A.; Noy, N. F.; Shah, N. H.; Whetzel, P. L.; Chute, C. G.; Story, M. -A.; Smith, B.; And The Ncbo, T. (2011). "The National Center for Biomedical Ontology" . Journal of the American Medical Informatics Association . 19 (2): 190– 195. doi :10.1136/amiajnl-2011-000523 . PMC 3277625 . PMID 22081220 .
^ Rubin, D. L.; Lewis, S. E. ; Mungall, C. J.; Misra, S.; Westerfield, M.; Ashburner, M. ; Sim, I.; Chute, C. G.; Storey, M. A.; Smith, B.; Day-Richter, J.; Noy, N. F.; Musen, M. A.; Musen, M. A. (2006). "National Center for Biomedical Ontology: Advancing Biomedicine through Structured Organization of Scientific Knowledge" (PDF) . OMICS: A Journal of Integrative Biology . 10 (2): 185– 198. doi :10.1089/omi.2006.10.185 . PMID 16901225 . S2CID 14097452 .
^ Botstein, D. ; Cherry, J. M.; Ashburner, M. ; Ball, C. A.; Blake, J. A.; Butler, H.; Davis, A. P.; Dolinski, K.; Dwight, S. S.; Eppig, J. T.; Harris, M. A.; Hill, D. P.; Issel-Tarver, L.; Kasarskis, A.; Lewis, S. ; Matese, J. C.; Richardson, J. E.; Ringwald, M.; Rubin, G. M. ; Sherlock, G. (2000). "Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium" . Nature Genetics . 25 (1): 25– 29. doi :10.1038/75556 . PMC 3037419 . PMID 10802651 .
^ Eilbeck, K.; Lewis, S. E. ; Mungall, C. J.; Yandell, M.; Stein, L. ; Durbin, R. ; Ashburner, M. (2005). "The Sequence Ontology: A tool for the unification of genome annotations" . Genome Biology . 6 (5): R44. doi :10.1186/gb-2005-6-5-r44 . PMC 1175956 . PMID 15892872 .
^ Mungall, C. J.; Torniai, C.; Gkoutos, G. V.; Lewis, S. E. ; Haendel, M. A. (2012). "Uberon, an integrative multi-species anatomy ontology" . Genome Biology . 13 (1): R5. doi :10.1186/gb-2012-13-1-r5 . PMC 3334586 . PMID 22293552 .
^ Carbon S, Ireland A, Mungall CJ, Shu S, Marshall B, Lewis S; AmiGO Hub; Web Presence Working Group (2008). "AmiGO: Online access to ontology and annotation data" . Bioinformatics . 25 (2): 288– 289. doi :10.1093/bioinformatics/btn615 . PMC 2639003 . PMID 19033274 . {{cite journal }}
: CS1 maint: multiple names: authors list (link )
^ Day-Richter, J.; Harris, M. A.; Haendel, M.; Lewis, S. (2007). "OBO-Edit an ontology editor for biologists". Bioinformatics . 23 (16): 2198– 2200. doi :10.1093/bioinformatics/btm112 . PMID 17545183 .
International National Academics