As part of setting up the school, SST partnered with Nanyang Technological University, IBM, and Creative Technology to provide learning opportunities and internship programmes for students.[6][7] Five new applied subjects were also designed in collaboration with NP to be taken at O-Levels, namely fundamentals of electronics, media studies and digital video production, design studies, biotechnology, and environmental science and technology. Students could take up to two applied subjects, on top of the regular O-Level subjects.[4][8][9]
Shortly after the announcement of its establishment, recruitment for teachers began on 17 March 2008.[10] In June 2008, Chua Chor Huat, former principal of Ngee Ann Secondary School, was appointed as the first principal, and Su Guaning was appointed as the first chairman.[6]
On 13 May 2009, SST began its inaugural intake via the Direct School Admissions scheme, receiving applications from more than 1,100 students.[11][12][13] An entrepreneurship advisory council, chaired by Inderjit Singh, was also set up to promote entrepreneurship and innovation in the school.[14][15]
On 4 January 2010, the school welcomed the inaugural batch of 200 students at its interim campus at 5 Clementi Avenue 6.[13]
On 29 March 2010, Senior Minister of State of National Development and Education Grace Fu officiated the groundbreaking ceremony for the permanent campus at 1 Technology Drive. Ngee Ann Kongsi also donated S$8.1 million to SST for annual scholarships and bursaries.[16][17]
SST offers a four-year science and technology curriculum, leading to O-Levels or first year entry to a STEM-related diploma course at NP. Apart from the regular O-Level subjects, students can take up to two additional applied subjects.[9] The first batch of O-Level students graduated in 2013.[3]
On 17 November 2020, Minister for Education Lawrence Wong announced the launch of the Integrated Diploma Programme (IDP) scheme, allowing students to bypass O-Levels and gain first year entry to any of the 21 STEM-related diploma courses offered at NP. Under this scheme, students will still need to take the mother tongue language subject for O-Levels, as required by the Ministry of Education. The first batch of IDP students will begin lessons at NP in April 2025.[18][19][20]