The program premiered on April 24, 2004 with Cheryl Cosim as its host alongside ABS-CBN reporter Pier Pastor as one of its segment hosts. It won several awards from prestigious award-giving bodies like the Anak TV Seal in 2006 and 2007, KBP Golden Dove in 2007 and the USTv Students' Choice 2008 as Best Public Service program. It celebrated its 4th anniversary with their anniversary episodes, which featured recent scandals and controversies that rocked the medical community.[1]
In August 2011, Alvin Elchico joins Sembrano as the new host of the show.
Veteran news personality and celebrity mom, Jing Castañeda, also joined the team as Program Host in December 2012, taking care of family issues/health, as well as the show's medical missions and healthy cooking segment.
On March 30, 2019, it aired its final episode on Saturday to give way for the 2 News and Current Affairs programs of ABS-CBN, namely: Mission Possible and My Puhunan.
the current status of the program. remained unknown until it was eventually cancelled on March 15, 2020 due to temporary closure of ABS-CBN because of the cease and desist order of the National Telecommunications Commission (NTC), following the expiration of the network's 25-year franchise granted in 1995.
The show resumed thru online and social media platforms as Thank You, Doc! on November 24, 2020.
