Propargite

Propargite[1][2]
Skeletal formula
Space-filling model
Names
IUPAC name
2-(4-tert-butylphenoxy)cyclohexyl prop-2-yne-1-sulfonate
Other names
Omite, Comite, Uniroyal D014
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.017.279 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3
  • O=S(OCC#C)OC2CCCCC2Oc1ccc(cc1)C(C)(C)C
Properties
C19H26O4S
Molar mass 350.47 g·mol−1
Appearance dark amber viscous liquid
Density 1.10 g/cm3
0.5 ppm
Solubility miscible in organic solvents
Hazards
Safety data sheet (SDS) Cornell University
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Propargite (IUPAC name 2-(4-tert-butylphenoxy)cyclohexyl prop-2-yne-1-sulfonate, trade names Mitex, Omite and Comite) is a pesticide used to kill mites (an acaricide).[2] It acts through inhibition of mitochondrial ATP synthase, and is in IRAC group 12C.[3] Symptoms of excessive exposure are eye and skin irritation, and possibly sensitization. It is highly toxic to amphibians, fish, and zooplankton, as well as having potential carcinogenity.[4]

References

  1. ^ Lide, David R. (1998), Handbook of Chemistry and Physics (87 ed.), Boca Raton, Florida: CRC Press, pp. 3–482, ISBN 978-0-8493-0594-8
  2. ^ a b "propargite (Omite, Comite) Chemical Fact Sheet 9/86". Cornell University. 1986-09-30. Retrieved 2009-12-02.
  3. ^ Kadir, Habsah A.; Knowles, Charles O. (1 June 1991). ", Inhibition of ATP Dephosphorylation by Acaricides with Emphasis on the Anti-ATPase Activity of the Carbodiimide Metabolite of Diafenthiuron". Journal of Economic Entomology. 84 (3): 801–805. doi:10.1093/jee/84.3.801.
  4. ^ "Integrated Risk Information System". 2013-03-15.

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2011.2087/epdf

  • Propargite in the Pesticide Properties DataBase (PPDB)


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