Pithecopus oreades inhabits open Cerrado savanna with short and scattered shrubs at elevations above 900 m (3,000 ft) above sea level. Breeding takes place in small streams and the tadpoles develop in pools within the streams. Threats to this species are unknown.[1]
P. oreades skin secretions research has suggested therapeutic value, especially as an anti-Trypanosoma cruzi agent to prevent infections during blood transfusion.[3]
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