Peter M. Howley

Peter M. Howley
EducationDoctor of Philosophy Edit this on Wikidata
OccupationVirologist, university teacher, pathologist, researcher, physician, senior lecturer Edit this on Wikidata
Employer
Awards

Peter Maxwell Howley (born October 9, 1946)[1] is an American pathologist,[2] virologist, and professor at Harvard Medical School.[3] He has been president of the American Society for Virology and the American Society for Investigative Pathology and a co-editor of the Annual Review of Pathology: Mechanisms of Disease.

Biography

Howley was born in New Brunswick, New Jersey. He graduated in 1968 from Princeton University with an A.B. in chemistry and in 1970 from Rutgers University with an M.M.S. (Master of Medical Science) degree. In 1972 he graduated with an M.D. from Harvard Medical School. From 1972 to 1973 he worked as an intern in pathology at Massachusetts General Hospital. He was a research associate from 1973 to 1975 at the National Institute of Allergy and Infectious Diseases (NIAID) in Bethesda, Maryland. In 1977 he was granted board certification in anatomic pathology. At the NCI's Laboratory of Pathology, Howley was from 1975 to 1976 a resident, from 1976 to 1977 a junior staff pathologist, from 1977 to 1979 a senior investigator, and from 1979 to 1984 Chief of the Viral Oncology and Molecular Pathology Section. From 1984 to 1993 he was Chief of the NCI's Laboratory of Tumor Virus Biology. In 1991, Howley became the George Fabyan Professor of Comparative Pathology at Harvard Medical School.[4] He was the president of the American Society for Virology from 1998 to 1999[5] and the president of the American Society for Investigative Pathology in 2006.[6] By 2009 he was the Shattuck Professor of Pathology.[7]

Howley is considered to be a leader in research on papillomaviruses. Howley and his co-workers created gene maps of many species of papillomaviruses and analyzed their transcription patterns and systems of transcription regulation. The research identified papillomavirus oncogenes and the molecular mechanisms of their damaging effects. This work is considered fundamental for the understanding of the pathogenesis of papillomaviruses at the molecular level.[8]

His research also involves assessing the roles of the E6AP/UBE3A ubiquitin ligase in human neurogenetic disorders.[8]

Peter M. Howley and David M. Knipe have been co-editors-in-chief, since the 3rd edition, of Fields Virology, a standard work on virology, with 5th edition published in 2006 and 6th edition published in 2013. Howley is also one of the chief editors of The Molecular Basis of Cancer, published by Elsevier.[9][10] He was a co-editor of the Annual Review of Pathology: Mechanisms of Disease from 2007–2015.[11] He is a member of the editorial board of the Proceedings of the National Academy of Sciences.[8]

He is married with three children.[1]

Peter M. Howley should not be confused with Paul M. Howley, who is a managing director of the vaccine biotechnology firm VAXMED Pty Ltd in Melbourne, Australia.[12]

Awards and honors

Selected publications

References

  1. ^ a b "Curricum Vitae: Peter M. Howley, M.D." Tobacco Documents Online. Archived from the original on 2014-08-22.
  2. ^ "Peter M. Howley, MD". DF/HCC Dana-Farber/Harvard Cancer Center.
  3. ^ "BBS Faculty Member - Peter Howley". BBS PhD Program in Biological and Biomedical Sciences, Harvard Medical School (hms.harvard.edu).
  4. ^ Harvard University History of Named Chairs: Sketches of Donors and Donations 1991 – 2004 (PDF). Cambridge, Massachusetts: Harvard University. 2005. pp. 100–103.
  5. ^ "Presidents of The American Society for Virology". American Society for Virology. Retrieved 4 October 2021.
  6. ^ "Past Officers of ASIP (Formerly the American Association of Pathologists)". American Society for Investigative Pathology (ASIP). Retrieved 4 October 2021.
  7. ^ "The 2009 Harvard / Paul F. Glenn Symposium on Aging June 8, 2009" (PDF). Paul F. Glenn Laboratories at Harvard Medical School.
  8. ^ a b c "Peter M Howley, MD". The Vallee Foundation.
  9. ^ Mendelsohn, John; Howley, Peter M.; Israel, Mark A.; Gray, Joe W.; Thompson, Craig B., eds. (1 April 2008). The Molecular Basis of Cancer: Expert Consult - Online. Elsevier Health Sciences. ISBN 978-1-4377-1099-1.
  10. ^ Mendelsohn, J.; Howley, P. M.; Israel, M. A.; Gray, J. W.; Thompson, C. B., eds. (2014). The Molecular Basis of Cancer E-Book. Elsevier Health Sciences. ISBN 978-0-323-26196-8.
  11. ^ "Annual Review of Pathology: Mechanisms of Disease. Volume 2: 2007. Edited by Abul K Abbas, , Stephen J Galli, and , Peter M Howley. Palo Alto (California): Annual Reviews. $55.00. Xii + 429 p; ill.; no index. ISBN: 978-0-8243-4302-6. 2007". The Quarterly Review of Biology. 82 (3): 311. 2007. doi:10.1086/523214.
  12. ^ Prow, Natalie A.; Liu, Liang; McCarthy, Mary K.; Walters, Kevin; Kalkeri, Raj; Geiger, Jillian; Koide, Fusataka; Cooper, Tamara H.; Eldi, Preethi; Nakayama, Eri; Diener, Kerrilyn R.; Howley, Paul M.; Hayball, John D.; Morrison, Thomas E.; Suhrbier, Andreas (2020). "The vaccinia virus based Sementis Copenhagen Vector vaccine against Zika and chikungunya is immunogenic in non-human primates". npj Vaccines. 5 (1): 44. doi:10.1038/s41541-020-0191-8. ISSN 2059-0105. PMC 7265471. PMID 32550013.
  13. ^ Howley, P. M. (1983). "The molecular biology of papillomavirus transformation. Warner-Lambert Parke-Davis Award Lecture". The American Journal of Pathology. 113 (3): 414–421. PMC 1916352. PMID 6316792.
  14. ^ Cotran, R. S. (1998). "Forty Years of the Warner-Lambert/ Parke-Davis Award : A Remarkable Record". The American Journal of Pathology. 153 (4): 1014. doi:10.1016/S0002-9440(10)65644-1. PMC 1853043. PMID 9777931.
  15. ^ "Wallace P. Rowe Award Plaque". Office of History, National Institutes of Health.
  16. ^ "Peter M. Howley, MD". American Society for Clinical Investigation.
  17. ^ "Peter M. Howley". National Academy of Sciences (nasonline.org).
  18. ^ "Goethe-Universität — Preisträger seit 1952 (prizewinners since 1952)". Uni-frankfurt.de (in German).
  19. ^ "Book of Members 1780—present, Chapter H" (PDF). American Academy of Arts and Sciences.
  20. ^ "ASIP Rous-Whipple Award". American Society for Investigative Pathology.
  21. ^ "Event Release - May 2011, News Publications". Robert Wood Johnson Medical School, Rutgers University.
  22. ^ "2015 Recipients of NCI Outstanding Investigator Awards - NCI". National Cancer Institute. 14 October 2015. Retrieved 14 June 2023.