In 2003, the hospital opened the Ortenzio Heart Center, a four-story, 140,000-square-foot (13,000 m2) facility located adjacent to the hospital specializing in the diagnosis and treatment of heart problems.[4]
Holy Spirit Health System, provides comprehensive inpatient and outpatient services and includes a regional network of six family health centers, one internal medicine office, a pediatric practice and two women's health centers.[2] The health system employs over 550 physicians in a variety of specialties to include women's health, cardiovascular care and orthopedic, stroke, and rehabilitative services.[5] Holy Spirit is a Level III Neonatal intensive-care unit.[2] Physician residency programs, affiliated with Memorial Hospital in York, Pennsylvania, exist on-site for emergency medicine and surgery.[6]
On September 9, 2013, Holy Spirit Health System signed a letter of intent with Geisinger Health System,[7] On September 1, 2017, Geisinger Holy Spirit was granted Level II Trauma Center accreditation by the Pennsylvania Trauma Systems Foundation.[8] Geisinger Holy Spirit was formerly called Holy Spirit Hospital. The hospital's name was changed as part of a rebranding campaign in 2017.[9]
On November 1, 2020, Holy Spirit was acquired by Penn State Health, including its medical group and ambulance service.[10]