Janak is an investigator in the field of the biological basis of behavior working on associative learning.[7][15] Her work empirically bridges formal learning theories and systems neuroscience in the mammalian brain. Using models based on theories of learning in combination with laboratory experiments,[16] Janak investigates associative processes and the hierarchical organization of relational and representational neural encoding.[17]Electrophysiological recordings from neurons in defined circuits are done using pharmacological and neurophysiological tools to manipulate circuit properties.[18][19] She has a demonstrated interest in a translational[20][21] approach to clinical conditions.[22][23] The fundamental aspects of learning and memory in the models she studies are basic to a broad range of human behaviors and can serve as a guide to intervention and therapies when capacities fail to develop normally or break down through disease.[24][25] Her most cited article,[26] titled, "A causal link between prediction errors, dopamine neurons and learning," was published in 2013 in Nature Neuroscience.[27]
Janak has 102 total publications, including 11 review papers, with more than 3300 total citations and an H index of 38.[26] She has been a member of the Society for Neuroscience since 1987 and the Research Society on Alcoholism since 1994.[28] Janak has taught both undergraduate and graduate courses on a variety of topics including psychology, data analysis, behavioral neuroscience, and drug addiction. At Johns Hopkins, Janak is teaching graduate psychology and neuroscience courses and an undergraduate course on learning and memory,[2] and actively participating in the interdisciplinary Science of Learning Institute.[29][30]
Publications
Janak has more than 15,000 citations in Google Scholar and an h-index of 68.[31]
2015 with KM Tye, From circuits to behaviour in the amygdala, in: Nature. Vol. 517, nº 7534; 284–292.
2013 with EE Steinberg, R Keiflin, JR Boivin, IB Witten, K Deisseroth, A causal link between prediction errors, dopamine neurons and learning, in: Nature Neuroscience. Vol. 16, nº 7; 966–973.
2011 with IB Witten, EE Steinberg, SY Lee, TJ Davidson, KA Zalocusky, M Brodsky, et al., Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement, in: Neuron. Vol. 72, nº 5; 721–733.
2012 with LH Corbit, H Nie, Habitual alcohol seeking: time course and the contribution of subregions of the dorsal striatum, in: Biological Psychiatry. Vol. 72, nº 5; 389–395.
2004 with NNH McGough, DY He, ML Logrip, J Jeanblanc, K Phamluong, K Luong, V Kharazia, D Ron, RACK1 and brain-derived neurotrophic factor: a homeostatic pathway that regulates alcohol addiction, in: Journal of Neuroscience. Vol. 24, nº 46; 10542–10552.
2015 with R Keiflin, Dopamine prediction errors in reward learning and addiction: from theory to neural circuitry, in: Neuron. Vol. 88, nº 2; 247–263.