The story follows Jayanta, a poor doctor, who falls in love with Mallika, the granddaughter of a wealthy man. Mallika helps Jayanta by giving him her mother's jewellery in order to fund his study of medicine in Europe. However, her grandfather, who is against their relationship, creates misunderstandings between the two and plans to wed Mallika off to another man. Things change when Jayanta comes back to find Mallika in a psychotic vegetative state resulting out of the anxiety and depression of being estranged from him. He sets out on a mission to devote all his life to cure her.
Robin Chatterjee composed the songs for the film and Gouri Prasanna Majumdar has written the lyrics. The songs became very popular and are famous even today. They are considered as timeless classics.
This was a milestone film for Bengali Cinema. This was the first ever color Bengali film in history shot in Gravacolor. But now only the black and white print is available.[12] The film received mixed reviews at that time. The Times of India wrote With their sheer charisma and chemistry, Uttam-Suchitra used to beat any other on-screen couple hollow. Their classic romantic films together are a treat to watch even today and ‘Pathey Holo Deri’ seems to be no exception.[13] The film become all-time blockbuster and ran for 100 days in the theaters.