Zuckerman's television career began when she worked as a writer/producer on the short-lived American telenovelaDesire, which ran from September 5, 2006 until December 5, 2006.
She worked as a story editor on another Fox series, Human Target and again co-wrote one episode, entitled "Dead Head", with her sister and Dan E. Fesman, based on a story by Tom Spezialy.
Nora and Lilla Zuckerman went on to write and produce on two seasons of the USA television series, Suits, then became co-executive producers on Agents of S.H.I.E.L.D. for seasons four through seven, writing multiple episodes. They then went on to be writers and co-executive producers of Prodigal Son for both seasons of its run.
Zuckerman and her sister are the showrunners and executive producers of Poker Face, a Peacock mystery crime drama created by Rian Johnson and starring Natasha Lyonne. It was met with critical acclaim upon its January 2023 release.[3]