Nils Kristian Lysø (born 3 September 1905 in Jøssund, died 7 July 1977) was a Norwegian politician for the Labour Party.
He was elected to the Norwegian Parliament from Sør-Trøndelag in 1958, and was re-elected on one occasion. He had previously served as a deputy representative during the terms 1950–1953 and 1954–1957.
On the local level he was a member of Jøssund municipality council from 1936 to 1954, serving as mayor from 1945 to 1953. From 1945 to 1955 he was also a member of Sør-Trøndelag county council. His political career ended with the position of County Governor of Sør-Trøndelag, which he held from 1963 to 1974.