He went to school in West Berlin and in Grünstadt (Western Germany) and was ordained a minister of the Protestant church of the Palatinate. In 1973 he received a PhD degree in Systematic Theology in Tübingen, Prof. Moltmann having been his advisor. In 1978 he received another PhD degree under supervision of the philosopher Prof. Henrich. In 1980 he completed his Habilitation in Tübingen, with his discussion of Whitehead and process philosophy. From 1983 to 1987 he was professor for Systematic Theology in Tübingen, 1987–1991 he held the chair for Reformed Theology in Münster, and from 1991 to 2013 he was a professor for dogmatics in Heidelberg. Since 2013 he has been a senior professor at Heidelberg University and, since 2005, managing director of the Forschungszentrum Internationale und Interdisziplinäre Theologie (FIIT) in Heidelberg, which he co-founded.
He lectured at the University of Chicago (1984), McMaster University (1985), Princeton Theological Seminary (1988 and 1995), the Center of Theological Inquiry, Princeton (1997, 1999), and at Harvard Divinity School (2001). In 2003 he was offered the position of the director of the Center of Theological Inquiry (CTI) in Princeton. 1996–2006 he was director of the Internationales Wissenschaftsforum Heidelberg (IWH). The University of Debrecen awarded him an honorary PhD degree, and so did the South African North-West University in Potchefstroom.
From 2004 to 2016 he was a member of the chamber of theology of the council of the Protestant Church in Germany (EKD) and judge at the constitutional court of the EKD; since 2006 he has been a regular member of the Heidelberg Academy of Sciences and an affiliated member of the Finnish Academy of Arts and Letters. He was granted the Medal of Heidelberg University. Since 1984 he has given lectures in the USA, in several European countries, Korea, China, South Africa and Brazil; since 1991 he has given numerous endowed lectures (Harvard, Princeton, Yale, Chicago, Edinburgh, Beijing, Taipei, Canberra among others).
During his commitment with the IWH and the CTI he organized numerous projects of international and interdisciplinary cooperation, research projects extended over several years, publications, especially concerning the dialog between theology and the sciences, and he still does so in connection with the FIIT. Since 2006 he has been building a Global Network of Research Centers for Theology, Religious and Christian Studies.
——— (2000). The End of the World and the Ends of God: Science and Theology on Eschatology. Harrisburg, PA: Trinity Press International. ISBN9781563383120. OCLC42923579.
———; Witte, John; Pickard, Stephen, eds. (2020). The Impact of Religion on Character Formation, Ethical Education, and the Communication of Values in Late Modern Pluralistic Societies. Leipzig: Evangelische Verlagsanstalt / Wipf & Stock. ISBN978-3-374-06410-6.
———; von Hagen, Jürgen; Witte, John; Pickard, Stephen, eds. (2020). The Impact of the Market on Character Formation, Ethical Education, and the Communication of Values in Late Modern Pluralistic Societies. Leipzig: Evangelische Verlagsanstalt / Wipf & Stock. ISBN978-3-374-06406-9.
———; Witte, John, eds. (2021). The Impact of the Law on Character Formation, Ethical Education, and the Communication of Values in Late Modern Pluralistic Societies. Leipzig: Evangelische Verlagsanstalt / Wipf & Stock. ISBN978-3-374-06801-2.
———; Schweiker, William; Witte, John; Pickard, Stephen, eds. (2021). The Impact of Academic Research on Character Formation, Ethical Education, and the Communication of Values in Late Modern Pluralistic Societies. Leipzig: Evangelische Verlagsanstalt / Wipf & Stock. ISBN978-3-374-06803-6.
———; Witte, John; Pickard, Stephen, eds. (2022). The Impact of the Family on Character Formation, Ethical Education, and the Communication of Values in Late Modern Pluralistic Societies. Leipzig: Evangelische Verlagsanstalt / Wipf & Stock. ISBN978-3-374-07052-7.
———; Pickard, Stephen; Witte, John, eds. (2022). The Impact of Education on Character Formation, Ethical Education, and the Communication of Values in Late Modern Pluralistic Societies. Leipzig: Evangelische Verlagsanstalt / Wipf & Stock. ISBN978-3-374-06801-2.
———; von Hagen, Jürgen; Witte, John; Pickard, Stephen, eds. (2022). The Impact of the Media on Character Formation, Ethical Education, and the Communication of Values in Late Modern Pluralistic Societies. Leipzig: Evangelische Verlagsanstalt / Wipf and Stock. ISBN978-3-374-07189-0.
———; Pickard, Stephen; Witte, John, eds. (2022). The Impact of the Military on Character Formation, Ethical Education, and the Communication of Values in Late Modern Pluralistic Societies. Leipzig: Evangelische Verlagsanstalt / Wipf and Stock. ISBN978-3-374-07187-6.
———; Winkler, Eva; Witte, John; Pickard, Stephen, eds. (2023). The Impact of Health Care on Character Formation, Ethical Education, and the Communication of Values in Late Modern Pluralistic Societies. Leipzig: Evangelische Verlagsanstalt / Wipf and Stock. ISBN978-3-374-07304-7.
———; Naudé, Piet; Witte, John, eds. (2023). The Impact of Political Economy on Character Formation, Ethical Education, and the Communication of Values in Late Modern Pluralistic Societies. Leipzig: Evangelische Verlagsanstalt / Wipf and Stock. ISBN978-3-374-07306-1.