*Club domestic league appearances and goals, correct as of 23:34, 14 December 2024 (UTC) ‡ National team caps and goals, correct as of 20 November 2023
On 30 June 2013, Pescara signed Politano (€500,000) and Piscitella (€1.5 million) as part of the deal that Caprari returned to Roma (€2 million);[6][7][8][9] however, Caprari returned to Pescara again (€1.5 million) for Piscitella (€1.5 million) in January 2014.
On 27 June 2015, Roma bought back Politano for €601,000, with Caprari moving to Pescara outright for €125,000.[10][11]
Sassuolo
On 2 July 2015, Serie A club Sassuolo signed Politano in a temporary deal with an option to purchase.[12] In June 2016, Sassuolo exercised their option to buy Politano.
Inter Milan
On 30 June 2018, Politano signed for Inter Milan on a season-long loan deal from Sassuolo, with an option to buy in June 2019.[13]
He made his official debut for the club on 19 August in the first match of 2018–19 Serie A against his parent club Sassuolo, which ended in a 1–0 away loss.[14] On 15 September, Politano played his 100th Serie A match in a 1–0 shock loss to Parma at home.[15] Two weeks later, he made his debut in the UEFA Champions League in a 2–1 comeback win over Tottenham Hotspur at San Siro in the first group stage match.[16]
On 29 September, he opened his scoring account for Inter in the league match against Cagliari, netting the second with a long-range strike in a 2–0 home win.[17] During the course of 2018–19 season, Politano was the most used out-field player, having made 48 appearances in all competitions; only goalkeeper Samir Handanović playing more than him. As a result, on 19 June 2019 Inter exercised their option to buy Politano from Sassuolo.[18]
However, with the appointment of head coach Antonio Conte and subsequent switch of formation from 4–3–3 to 3–5–2, Politano soon lost his place in the team's usual starting line-up.[19] In January 2020, Politano passed the medical at Roma and was due to be exchanged for Leonardo Spinazzola yet the transfer collapsed as Inter were not entirely satisfied with Spinazzola's physical conditions and failed at re-negotiation of the deal.[20]
Napoli
On 28 January 2020, Politano moved to Napoli on a two-year loan with an obligation to make deal permanent.[21] On 29 October 2020, he scored the only goal in a 1–0 away win over Real Sociedad in the 2020–21 UEFA Europa League.[22]
Politano is a quick and diminutive left-footed player, with an eye for goal, who is gifted with pace, vision, good technique, and dribbling ability at speed, as well as good close control and first-time passing ability in close spaces.[13] A versatile player, he is usually deployed as a winger, and is capable of playing on either flank, as well as in numerous other attacking roles across the front line, including as a second striker.[27] He also possesses a good shot from distance, and is a threat from set-pieces.[28]
Married in June 2018 to Silvia Di Vincenzo, he later became engaged to PR Ginevra Sozzi.[31] On June 17, 2021, their first daughter, Giselle, was born.[32]