While studying, Nair modelled, appearing in various advertisements as well as the Mohan Sithara-directed music video, "Rithukkal". She subsequently began to receive acting offers and eventually entered the film industry at age 13.[5] In her first few films she had minor supporting or cameo roles; in Ustad Hotel, she made a brief appearance in a song sequence,[6] while in Puthiya Theerangal and Karmayodha she played the daughter of Nedumudi Venu and Mohanlal's characters, respectively.[2] Her first major role was as Reena, a house maid who faces an acid attack, in the Malayalam drama film Black Butterfly (2013), a remake of Vazhakku Enn 18/9.[7]
After watching her performance in Black Butterfly, Balaji Sakthivel, director of its original version, was impressed and recommended aspiring director Raju Murugan to cast her in his romantic drama film Cuckoo (2014).[2] She portrayed an independent blind girl in the film and prior to the shoot, attended a workshop where she interacted with blind people.[8] Pairing alongside Dinesh, Malavika portrayed Sudhanthirakodi and won critical acclaim for her portrayal. Behindwoods noted her as "effectuated excellence", while Sify.com's review stated she was "superb" and that she "lives the role".[9][10] Her performance was subsequently rewarded with the Filmfare Award for Best Actress, Vijay Award for Best Debut Actress[citation needed] as well as the SICA Award for Best Newcomer and the Vikatan Award for Best Actress.[11] Prior to Cuckoo, she had a Malayalam release, Pakida, in which she portrayed a fifteen-year-old girl who is sold to a brothel by her own father.[6]
Nair next appeared in the Telugu film Yevade Subramanyam (2015) alongside Nani, with a critic noting she "shows a lot of spunk and comes up with a matured performance for a newcomer".[12] Malavika's next release was the romantic drama, Kalyana Vaibhogame (2016), opposite Naga Shaurya. It was directed by B. V. Nandini Reddy and the film was praised and her role was well appreciated. Sify wrote that "Malavika Nair who wowed the audiences with her performance in Yevade Subramanyam shines again as modern independent minded girl. She steals the show in many scenes".[13]
In 2018, she starred as Alamelu Gemini Ganeshan in the Savitri biopic, Mahanati, directed by Nag Ashwin, which was successful at the box-office ran of 100 days.[14]
^Certain award groups do not simply award one winner. They acknowledge several different recipients, have runners-up, and have third place. Since this is a specific recognition and is different from losing an award, runner-up mentions are considered wins in this award tally. For simplification and to avoid errors, each award in this list has been presumed to have had a prior nomination.