Malvern Panalytical

Malvern Panalytical
Company typePrivate Limited Company
IndustryInstrumentation
FoundedMalvern, Worcestershire, United Kingdom 1971
Headquarters
Malvern, Worcestershire, United Kingdom; Almelo, Netherlands
Key people
Mark Fleiner, President[1]
RevenueGBP 448.2 million (2019)
Number of employees
Globally: 2,400
ParentSpectris
Websitewww.malvernpanalytical.com
Footnotes / references

Malvern Panalytical is a Spectris plc company.[6] The company is a manufacturer and supplier of laboratory analytical instruments.[7][8] It has been influential in the development of the Malvern Correlator,[9] and it remains notable for its work in the advancement of particle sizing technology.[10] The company produces technology for materials analysis and principal instruments designed to measure the size, shape and charge of particles.[11] Additional areas of development include equipment for rheology measurements,[3][12] chemical imaging[13] and chromatography.[14] In 2017, they merged with PANalytical to form Malvern Panalytical Ltd.[15]

History

Malvern Instruments Ltd. was incorporated in 1971.[14] In 1977, Malvern Instruments was recognised by the Royal Academy of Engineering, jointly with the Royal Signals and Radar Establishment (RSRE), for developing the Malvern Correlator.[6][16] It also received the MacRobert Award for Outstanding Technical Innovation (1977),[6] the Queen's Award for Technological Achievement (1977),[17] the Queen's Award for Export Achievement (1981),[17] and the Queen's Award for Export & Technology (1988).[17]

In 1992, Burnfield acquired Malvern Instruments from Cray Electronics Holdings,[18] and, in 1996, there was the acquisition of A3 Water Solutions GmbH, a Stuttgart-based specialist in the design, marketing, and manufacturing of air and liquid particle counters.[19] In 1997, Malvern was also acquired by the Fairey Aviation Company, and Insitec Inc from Burnfield PLC.[20]

The holding company changed its name to Spectris plc in 2001.[4] In 2003, they acquired Bohlin Instruments Ltd, a Gloucestershire-based manufacturer of rheology and viscosity instruments.[21] They also acquired Spectral Dimensions Inc, a manufacturer of infrared chemical imaging instruments, in 2006.[11] Malvern received the 2006 Queen's Award for International Trade.[22]

Viscotek Corp, manufacturer of chromatographic and laboratory equipment and supplies, was acquired in 2008,[10] as well as Reologica Instruments AB, a Lund-based manufacturer of rheology and viscometry instrumentation, in 2010.[3] Malvern received the 2010 Queen's Award for Innovation.[22] The company was also listed as a 2010 winner of the annual Queen's Awards for Enterprise for its work measuring particles in fluids.[2][23][24]

In 2013, they acquired NanoSight, a Wiltshire-based manufacturer of nanoparticle characterization instruments,[5] and, in 2014, the Northampton-based manufacturer of Thermodynamic analysis instruments, MicroCal Instruments, was acquired from GE Lifesciences.[25]

In 2017, they merged with PANalytical to form Malvern Panalytical Ltd.[15] That same year, Malvern Panalytical released their X-ray fluorescence (XRF) spectrometer Epsilon, which was specifically designed for small spot analysis.[26] In 2018, Malvern Panalytical unveiled Empyrean, the first fully automated multipurpose x-ray diffractometer;[27] Claisse LeDoser-12, an Automatic Dispensing Balance; Morphologi Range, a new morphologically-directed raman spectroscopy system, and Epsilon 4, a benchtop x-ray fluorescence spectrometer.[28]

Malvern Panalytical launched a new partnership with SCOTT Technology Ltd., a supplier of sample preparation equipment, in 2020.[29] Their contract included engineering a fully automated robotic analytical system, incorporating fusion bead sample preparation, implementing X-ray spectrometry instrumentation, and developing thermogravimetric analysis (TGA) equipment.[29] The company also joined partnership with Concept Life Sciences that year.[30] Netzsch acquired Malvern Panalytical’s rheometer product lines in February 2020.[31] In this acquisition, Malvern Panalytical extended Netzsch’s product portfolio by providing Kinexus rotational rheometers and Rosand capillary rheometers.[31] In September 2020, Malvern Panalytical received the Physikalisch-Technische Bundesanstalt (PTB) type approval, as a “full-protection” X-ray instrument, for its Aeris range of benchtop XRD diffractometers.[32]

Business model

Malvern Instruments began with a focus on particle sizing.[5] As it grew, this focus changed toward developing a "broad portfolio of analytical solutions".[5] In 2014, the company's CTO expressed the company's focus as "We want to solve analytical bottlenecks".[5]

In order to maintain agility and currency in product development, the company built an isolated internal division, the Bioscience Development Initiative based in Columbia, Maryland, which has an entrepreneurial character and freedom from corporate management constraints; the unit aims to rapidly develop technologies in partnership with scientists and engineers from the pharmaceutical and other industries and academia.[5] This unit focuses on the biopharmaceutical sector, specifically formulation of drug products.[5]

PANalytical originally began in 1948 as a branch of Philips under the name of Philips Analytical, which developed XRF (X-Ray Fluorescence) and XRD (X-Ray Diffraction) equipment.[33][34][35] In 2002, Philips Analytical was officially renamed to PANalytical after Spectris’ acquisition of this x-ray analytical branch.[34] Malvern later merged with PANalytical to become Malvern Panalytical Ltd. in 2017.[15]

Operations

As part of the materials analysis sector, Malvern Panalytical derives most of its revenue through sales of a range of particle and material characterisation instruments.[4] These systems have applications across many industries including: pharmaceuticals, life sciences, metallurgy, mining, semiconductors, polymer science, protein science and food production.[7][36][37]

Products

Malvern droplet and particle analyser

Full products include:

References

  1. ^ "Malvern Panalytical appoints Fleiner as its new president". Metal AM. 22 January 2020.
  2. ^ a b "Malvern Instruments Limited". Companies House (WebCheck). United Kingdom: Department for Business, Innovation and Skills. Company Number 01020602. Retrieved 2 December 2014.
  3. ^ a b c Staff (30 April 2010). "West Midlands Successes in the Queens Award for Enterprise". Birmingham Post. Archived from the original on 25 September 2012. Retrieved 10 June 2010.
  4. ^ a b c "Hoover report". Retrieved 14 May 2010.[dead link‍]
  5. ^ a b c d e f g Dutton, Gail (1 January 2014). "Traditional Instrument Maker Stays Nimble". Gen. Eng. Biotechnol. News. Vol. 31, no. 1. pp. 8–9.(registration required)
  6. ^ a b c d Groom, Brian (21 April 2010). "The cutting edge of enterprise stays sharp". Financial Times. United Kingdom.(subscription required)
  7. ^ a b "Malvern Instruments Ltd acquires Reologica Instruments AB". United States: Alacra. 14 April 2010. Archived from the original on 2 April 2011. Retrieved 12 June 2010.
  8. ^ "SPECTRIS PLC (SXS:London Stock Exchange): Stock Quote & Company Profile". United States: Bloomberg Businessweek. Archived from the original on 3 October 2012. Retrieved 14 June 2010.
  9. ^ "Past Winners". MacRobert Award. United Kingdom: Royal Academy of Engineering. 1977. Archived from the original on 7 May 2016. Retrieved 2 December 2014.
  10. ^ a b Provder, Theodore (2000). "Challenges in particle size distribution measurement past, present and for the 21st century". In Craver, Clara D.; Carraher, Charles E. Jr. (eds.). Applied Polymer Science: 21st Century. The Netherlands: Elsevier. pp. 873–92. doi:10.1016/B978-008043417-9/50043-X. ISBN 9780080434179.Closed access icon
  11. ^ a b "About Malvern Instruments". Malvern Instruments. Retrieved 2 December 2014.
  12. ^ "Malvern Instruments Ltd acquires Bohlin Instruments Ltd". United States: Alacra. 17 January 2008. Archived from the original on 16 January 2013. Retrieved 12 June 2010.
  13. ^ "Malvern Instruments Ltd acquires Spectral Dimensions Inc". United States: Alacra. 15 July 2006. Archived from the original on 16 January 2013. Retrieved 12 June 2010.
  14. ^ a b "Malvern Instruments Ltd acquires Viscotek Corp". United States: Alacra. 31 October 2003. Archived from the original on 2 April 2011. Retrieved 12 June 2010.
  15. ^ a b c "Malvern Instruments and PANalytical to merge". Analytica World. 2 December 2016.
  16. ^ "The Royal Academy of Engineering (RAE)".
  17. ^ a b c BINDT website, the British Institute of Non-Destructive Testing, http://www.bindt.org/Content.asp?PageID=999&RSSID=4 Archived 25 July 2011 at the Wayback Machine Retrieved 12 June 2010
  18. ^ Thomson Financial Mergers & Acquisitions report; Burnfield PLC acquires Malvern Instruments Ltd from Anite PLC, published 9 September 1992; Retrieved 12 June 2010
  19. ^ Thomson Financial Mergers & Acquisitions report; Malvern Instruments Ltd acquires A3 GmbH, published 1 November 1996; Retrieved 12 June 2010
  20. ^ Thomson Financial Mergers & Acquisitions report; Malvern Instruments Ltd acquires Insitec Inc from Burnfield PLC, published 31 March 1997; Retrieved 12 June 2010
  21. ^ a b Holoubek, Jaroslav (2007). "Some applications of light scattering in materials science". Journal of Quantitative Spectroscopy and Radiative Transfer. 106 (1–3): 104. Bibcode:2007JQSRT.106..104H. doi:10.1016/j.jqsrt.2007.01.013.
  22. ^ a b Queens Award for Enterprise Magazine; http://www.queensawardsmagazine.com/awardwinners/search?qchar=M Winners list Archived 5 October 2010 at the Wayback Machine Retrieved 12 June 2010
  23. ^ "The Queen's Awards for Enterprise".
  24. ^ "BINDT - Malvern Instruments celebrates fifth Queen's Award". Archived from the original on 25 July 2011. Retrieved 28 June 2010.{{cite web}}: CS1 maint: bot: original URL status unknown (link) Retrieved 12 June 2010
  25. ^ "Malvern Instruments to acquire MicroCal business from GE Healthcare Life Sciences". Virtual Expo Group. 2014.
  26. ^ "Malvern PANalytical Releases X-Ray Fluorescence Spectrometer". Pharmaceutical Technology. 18 July 2017.
  27. ^ "The New Empyrean - a Revolution in the World of X-ray Diffraction". Technology Networks. 3 July 2018.
  28. ^ "Malvern Panalytical launches new Morphologically-Directed Raman Spectroscopy system, Benchtop X-ray Fluorescence Spectrometer, and an Automatic Dispensing Balance at Pittcon 2018". European Pharmaceutical Review. 1 March 2018.
  29. ^ a b smith, betty (2 July 2020). "Malvern Panalytical gets automated robotic analytical system order from SCOTT for Rio's Koodaider". International Mining.
  30. ^ "Industry News: Malvern Panalytical and Concept Life Sciences combine experience and know-how in unique partnershipi". Select Science. 31 March 2020.
  31. ^ a b smith, betty (13 February 2020). "Netzsch Acquires Malvern Panalytical Rheometer Product Lines". ASI.
  32. ^ "Malvern Panalytical's Aeris Benchtop XRD Passes Stringent PTB Safety-Assessments". AZO Materials. 26 September 2020.
  33. ^ "Philips Analytical - a one stop characterization shop" (PDF). Elsevier Science Ltd. 1998.
  34. ^ a b "Philips To Sell Its X-Ray Analytical Business To Spectris". Laser Focus World. 22 July 2002.
  35. ^ "Suppliers of equipment and services". Crystallographic Resources.
  36. ^ Blakemore, S (2 July 2000). "Made in the Midlands". Sunday Mercury. United Kingdom.
  37. ^ Snowsill, W.L. (2010). "Particle Sizing". Instrumentation Reference Book. pp. 175–189. doi:10.1016/B978-0-7506-8308-1.00016-4. ISBN 9780750683081.
  38. ^ Simmons, Mark J.H; Hanratty, Thomas J. (May 2001). "Droplet size measurements in horizontal annular gas–liquid flow". International Journal of Multiphase Flow. 27 (5): 861–883. doi:10.1016/S0301-9322(00)00053-7.
  39. ^ Dumouchel, C.; Yongyingsakthavorn, P.; Cousin, J. (March 2009). "Light multiple scattering correction of laser-diffraction spray drop-size distribution measurements". International Journal of Multiphase Flow. 35 (3): 277–287. doi:10.1016/j.ijmultiphaseflow.2008.11.001.
  40. ^ Farina, Dino J. (2010). "Regulatory Aspects of Nasal and Pulmonary Spray Drug Products". Handbook of Non-Invasive Drug Delivery Systems. pp. 247–290. doi:10.1016/B978-0-8155-2025-2.10010-1. ISBN 9780815520252.
  41. ^ Johnson, William; Chen, Shulin (January 2006). "Performance evaluation of radial/vertical flow clarification applied to recirculating aquaculture systems". Aquacultural Engineering. 34 (1): 47–55. doi:10.1016/j.aquaeng.2005.05.001.
  42. ^ Couto, Hudson J.B.; Nunes, Daniel G.; Neumann, Reiner; França, Sílvia C.A. (March 2009). "Micro-bubble size distribution measurements by laser diffraction technique". Minerals Engineering. 22 (4): 330–335. Bibcode:2009MiEng..22..330C. doi:10.1016/j.mineng.2008.09.006.
  43. ^ Kwak, Byung-Man; Lee, Ji Eun; Ahn, Jang-Hyuk; Jeon, Tae-Hong (June 2009). "Laser diffraction particle sizing by wet dispersion method for spray-dried infant formula". Journal of Food Engineering. 92 (3): 324–330. doi:10.1016/j.jfoodeng.2008.12.005.
  44. ^ Abdelbary, G.; Prinderre, P.; Eouani, C.; Joachim, J.; Reynier, J.P; Piccerelle, Ph (8 July 2004). "The preparation of orally disintegrating tablets using a hydrophilic waxy binder". International Journal of Pharmaceutics. 278 (2): 423–43. doi:10.1016/j.ijpharm.2004.03.023. PMID 15196646. 3
  45. ^ "World News". Journal of the Association for Laboratory Automation. 15 (3): A18, A20 – A22, A24 – A28, A30 – A34, A36. June 2010. doi:10.1016/j.jala.2010.02.007. S2CID 208507681.
  46. ^ Pfrengle, A.; von Both, H.; Knitter, R.; Haußelt, J. (2006). "Electrophoretic deposition and sintering of zirconia layers on microstructured steel substrates". Journal of the European Ceramic Society. 26 (13): 2633–2638. doi:10.1016/j.jeurceramsoc.2005.05.014.
  47. ^ Yalamanchili, M.R.; Kellar, J.J.; Miller, J.D. (1993). "Adsorption of collector colloids in the flotation of alkali halide particles". International Journal of Mineral Processing. 39 (1): 137. Bibcode:1993IJMP...39..137Y. doi:10.1016/0301-7516(93)90058-I.
  48. ^ Chen, Yan; Flowers, Kaleyhia; Calizo, Milagros; Bishnoi, Sandra Whaley (1 March 2010). "The role of protein binding in the poisoning of gold nanoparticle catalysts". Colloids and Surfaces B: Biointerfaces. 76 (1): 241–247. doi:10.1016/j.colsurfb.2009.10.043. PMID 19939642.
  49. ^ a b "2830 ZT - Advanced Wavelength Dispersive XRF Analysis". AZO Materials.
  50. ^ a b "Axios FAST - The Fastest WDXRF Spectrometer on the Market". AZO Materials.
  51. ^ Storti, Fabrizio; Balsamo, Fabrizio (2010). "Impact of ephemeral cataclastic fabrics on laser diffraction particle size distribution analysis in loose carbonate fault breccia". Journal of Structural Geology. 32 (4): 507. Bibcode:2010JSG....32..507S. doi:10.1016/j.jsg.2010.02.006. Journal of Structural Geology, Volume 32, Issue 4, April 2010, Pages 507–522
  52. ^ Edwards, Alexander D.; Chatterjee, Pratichi; Mahbubani, Krishnaa T.; Reis, Cassilda M.; Slater, Nigel K.H. (2010). "Optimal protection of stabilised dry live bacteria from bile toxicity in oral dosage forms by bile acid adsorbent resins" (PDF). Chemical Engineering Science. 65 (16): 4844. Bibcode:2010ChEnS..65.4844E. doi:10.1016/j.ces.2010.05.030.
  53. ^ "Wall Colmonoy expands metal powder capabilities at European HQ's R&B Lab". Metal AM. 18 June 2020.
  54. ^ Komabayashi, Takashi; d'Souza, Rena N.; Dechow, Paul C.; Safavi, Kamran E.; Spångberg, Larz S.W. (February 2009). "Particle Size and Shape of Calcium Hydroxide". Journal of Endodontics. 35 (2): 284–287. doi:10.1016/j.joen.2008.11.017. PMC 2656936. PMID 19166791.
  55. ^ Raschke, D.; Knorr, D. (November 2009). "Rapid monitoring of cell size, vitality and lipid droplet development in the oleaginous yeast Waltomyces lipofer". Journal of Microbiological Methods. 79 (2): 178–183. doi:10.1016/j.mimet.2009.08.011. PMID 19723546.
  56. ^ Krause, Beate; Petzold, Gudrun; Pegel, Sven; Pötschke, Petra (March 2009). "Correlation of carbon nanotube dispersability in aqueous surfactant solutions and polymers". Carbon. 47 (3): 602–612. doi:10.1016/j.carbon.2008.10.040.
  57. ^ Li, Weiyong; Woldu, Abraham; Kelly, Richard; McCool, Jim; Bruce, Rick; Rasmussen, Henrik; Cunningham, John; Winstead, Denita (2008). "Measurement of drug agglomerates in powder blending simulation samples by near infrared chemical imaging". International Journal of Pharmaceutics. 350 (1–2): 369–73. doi:10.1016/j.ijpharm.2007.08.055. PMID 17951017.
  58. ^ Puchert T, Lochmann D, Menezes JC, Reich G (2010). "Near-infrared chemical imaging (NIR-CI) for counterfeit drug identification--a four-stage concept with a novel approach of data processing (Linear Image Signature)". Journal of Pharmaceutical and Biomedical Analysis. 51 (1): 138–45. doi:10.1016/j.jpba.2009.08.022. PMID 19766424.
  59. ^ Hilden LR, Pommier CJ, Badawy SI, Friedman EM (2008). "NIR chemical imaging to guide/support BMS-561389 tablet formulation development". International Journal of Pharmaceutics. 353 (1–2): 283–90. doi:10.1016/j.ijpharm.2007.11.032. PMID 18182257.
  60. ^ Luukkonen, Pirjo; Schæfer, Torben; Hellén, Leena; Juppo, Anne Mari; Yliruusi, Jouko (25 October 1999). "Rheological characterization of microcrystalline cellulose and silicified microcrystalline cellulose wet masses using a mixer torque rheometer". International Journal of Pharmaceutics. 188 (2): 181–192. doi:10.1016/s0378-5173(99)00219-7. PMID 10518674.
  61. ^ Allen, Kirsty E.; Murray, Brent S.; Dickinson, Eric (2008). "Whipped cream-like textured systems based on acidified caseinate-stabilized oil-in-water emulsions". International Dairy Journal. 18 (10–11): 1011–1021. doi:10.1016/j.idairyj.2008.04.003.
  62. ^ Jewad, Raeid; Bentham, Craig; Hancock, Bruno; Bonfield, William; Best, Serena M. (2008). "Dispersant selection for aqueous medium pressure injection moulding of anhydrous dicalcium phosphate". Journal of the European Ceramic Society. 28 (3): 547–553. doi:10.1016/j.jeurceramsoc.2007.07.010.
  63. ^ Hagenaars, Niels; Verheul, Rolf J.; Mooren, Imke; De Jong, Pascal H.J.L.F; Mastrobattista, Enrico; Glansbeek, Harrie L.; Heldens, Jacco G.M.; Van Den Bosch, Han; Hennink, Wim E.; Jiskoot, Wim (2009). "Relationship between structure and adjuvanticity of N,N,N-trimethyl chitosan (TMC) structural variants in a nasal influenza vaccine". Journal of Controlled Release. 140 (2): 126–133. doi:10.1016/j.jconrel.2009.08.018. PMID 19712713.
  64. ^ "Entry-Level Particle Size and Zeta Potential Analyzer with Enhanced Capabilitiesy". AZO Materials.
  65. ^ "Using Differential Scanning Calorimetry for Biosimilarity and Batch-to-Batch Comparability". News Medical Net. 21 April 2017.
  66. ^ "Malvern Panalytical's ASD Range". Analytik.
  67. ^ "Malvern Panalytical". Mining Technology.
  68. ^ "PFTNA Process Control for the Cement and Mining Industry - CNA Cross-Belt Analyzers". AZO Materials.
  69. ^ "The New Empyrean - a Revolution in the World of X-Ray Diffraction". Technology Networks. 3 July 2018.
  70. ^ "Epsilon 4 X-ray Fluorescence Spectrometer from Malvern Panalytical". News Medical Life Sciences.
  71. ^ "Insitec Dry Particle Size Analyzersy". AZO Materials.
  72. ^ "Particle Testing Authority (PTA) A Division Of Micromeritics Instrument Corporation Continues To Expand Its Capacity To Analyze A Wide Range Of Particles". Pharmaceutical Online. 29 October 2018.
  73. ^ "MicroCal PEAQ-ITC - The Gold Standard for Measuring Affinity and Stoichiometry". Technology Networks. 6 October 2020.
  74. ^ "NanoSight NS300 - Multi-Faceted Nanoparticle Analysis". AZO Nano.
  75. ^ smith, betty (16 January 2018). "Waters and Malvern Panalytical Collaborate to Improve Polymer Characterization". Businesswire.
  76. ^ "Parsum IPP 70 S". AZO Materials.
  77. ^ "Spraytec Laser Diffraction System". AZO Materials.
  78. ^ "X'Pert³ Powder Cost-Effective, Multipurpose X-ray Diffraction from PANalytical". AZO Mining.
  79. ^ "Zetasizer AT - On-Line Measurement of Particle Size Using DLS". AZO Materials.
  80. ^ "Multi-Functional XRF Platform - Zetium from PANalytical". AZO Nano.