Tisseyre studied kinesiology at Laval University and went on to obtain her master's degree in biomechanics at McGill University. While attending school she got involved with a local triathlon club where she discovered a love for the sport.[2] As an amateur she won the Canadian University Championship at the age of 23 and then won the 20-24 female age group at the 2005 ITU World Duathlon Championships.[3] In 2006 and 2007, she competed on the ITU triathlon and duathlon racing circuit.[4] Tisseyre also competed in cycling events where she competed in the Le Tour du Grand Montréal and finished second in the 2008 Mount Washington Auto Road Bicycle Hillclimb.[5]
In 2008 and 2009, Tisseyre began focusing on long distance triathlon and competing in various Ironman 70.3 distance races. At the end of 2009 she took third place at the Ironman 70.3 World Championship in Clearwater, Florida. Her efforts that year led to her being called Triathlete magazine's Ironman 70.3 Triathlete of the Year.[6] In 2010, she matched the previous year's finish with another third place.