Ayoub was born in Haifa, Israel. She is the daughter of an Arab-Christian father, and an Ashkenazi Jewish mother who converted to Christianity upon their marriage. Ayoub has one brother and three sisters.[4][5] Her paternal grandmother was the daughter of Palestinian refugees who fled to Lebanon during the 1948 Arab-Israeli War She was left in a convent in Israel, and later was adopted by a wealthy Arab-Christian woman named Lucy Khayat.[4] Her maternal grandparents were Holocaust survivors: her maternal grandfather was sent to a Nazi concentration camp, while her maternal grandmother from Romania survived among partisans as a child.[4] Ayoub celebrates both the Christian and Jewish holidays with different parts of her family although she says she is an atheist: "I’m an atheist and it means nothing to me that I was baptized [in church]".[6] She attended a Catholic Carmelites school in Haifa.[4] She wrote stories and poems in both Arabic and Hebrew.
She first gained public attention in 2016, when she read several pieces of her poetry in the framework of the Poetry Slam Israel competition. In the same year, she joined the Israeli Public Broadcasting Corporation (IPBC) and started writing and submitting videos. In 2017, Ayoub began to host a weekly cultural programme on the radio station. In the same year, she began hosting the daily TV programme Culture Club on Kan 11.
Ayoub speaks Arabic and Hebrew.[5] In a poem she says of her self-identity: "[S]ome of you will say I will always be the daughter of the Arab, and at the same time, in the eyes of others, I will always be the daughter of the Jewess. So do not suddenly tell me that I can not be both."[5]
^Jewish-Arab Slam Poet a Hit in Person and on YouTube By Shachar Atwan 29 June 2016: "I’m an atheist and it means nothing to me that I was baptized. On the other hand, culturally I like the atmosphere and spending the Christian holidays with my [nuclear] family. I celebrate Jewish holidays with my [maternal] grandmother and uncles.”