Lucimycin

Lucimycin

Identifiers
CAS Number	13058-67-8^Y
3D model (JSmol)	Interactive image
ECHA InfoCard	100.032.667
PubChem CID	6433568
UNII	3K1B4B63D0^Y
SMILES CCCCC1CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC3C(O3)C=CC(=O)O1)O)O)O)C(=O)O)OC4C(C(C(C(O4)C)O)N)O
Properties
Chemical formula	C36H53NO13
Molar mass	707.80492
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is ^YN ?) Infobox references

Lucimycin (INN, also known as lucensomycin and etruscomycin) is a macrolide antibiotic synthesized by the bacterium Streptomyces lucensis. It belongs to the group of polyene antimycotics and was first isolated in the 1960s. It has seen only limited clinical use.

Lucimycin is also produced by the Streptomyces cyanogenus S136, where the full biosynthetic gene cluster for the production of this compound was described.[1]

References

1. Yushchuk O, Ostash I, Mösker E, Vlasiuk I, Deneka M, Rückert C, et al. (February 2021). "Eliciting the silent lucensomycin biosynthetic pathway in Streptomyces cyanogenus S136 via manipulation of the global regulatory gene adpA". Scientific Reports. 11 (1): 3507. Bibcode:2021NatSR..11.3507Y. doi:10.1038/s41598-021-82934-6. PMC 7875965. PMID 33568768.

Further reading

• Ganellin CR, Macdonald F, Triggle DJ (1997). Dictionary of Pharmacological Agents. CRC Press. p. 1239. ISBN 9780412466304.