Lisa Jones (scientist)

Lisa Jones
Alma materSyracuse University
Georgia State University
Known forCell footprinting
Scientific career
InstitutionsUniversity of California, San Diego
University of Maryland
Indiana University-Purdue University Indianapolis
Washington University
University of Alabama at Birmingham
ThesisUsing Protein Design to Understand the Role of Electrostatic Interactions on Calcium Binding Affinity and Molecular Recognition (2008)
Doctoral advisorJenny J. Yang
Other academic advisorsMichael Gross
WebsiteOfficial website

Lisa Michelle Jones (born February 1977) is a professor of chemistry and biochemistry at the University of California, San Diego (UCSD).[1] Her research is in structural proteomics, using mass spectrometry (MS) together with fast photochemical oxidation of proteins (FPOP), allowing researchers to study the solvent accessibility of proteins experimentally.

Early life and education

Jones became interested in science as a freshman at high school, where she took part in a national Science Technology Engineering Program.[2] She earned a BS in biochemistry at Syracuse University in 1999.[3] Jones completed her PhD at Georgia State University and specialized in structural biology.[4]

Jones received postdoctoral training in structural virology at the University of Alabama at Birmingham. She was a Pfizer postdoctoral researcher at Washington University in St. Louis working with Michael Gross on MS-based protein footprinting developed by Maleknia and co-workers in the late 1990s.[5][6][2][7]

Research and career

After her postdoctoral research, she joined Indiana University, where she became an associate professor.[8][9] She moved to the University of Maryland School of Pharmacy in 2016.[10] In her research, Jones focusses on structural proteomics, having developed fast photochemical oxidation of proteins (FPOP) which uses an excimer laser for photolysis, which generates hydroxyl radicals. Hydroxyl radicals go on to oxidise the side chains of amino acids and provide solvent accessibility of proteins within a cell.[11] FPOP can provide information on the sites of ligand binding, protein interaction and protein conformational changes in vivo. More recently, her group has extended the platform with a no-flow platform for high-throughput in-cell measurements.[12]

In 2019, she received the Biophysical Society's Junior Faculty Award.[13]

Jones also works on science outreach and improving representation in the sciences. She is a mentor in the UMD CURE Scholars Program [14][15] and a member of the American Society for Mass Spectrometry Diversity and Outreach Working Group.[16] Jones is also co-director of the Initiative to Maximize Student Development (IMSD) Meyerhoff Graduate Fellowship Program, a program for increasing representation of minority students in STEM.[17]

In 2021, Jones was in the news for turning down a faculty position at the University of North Carolina Chapel Hill in protest of controversy regarding the tenure status of journalist Nikole Hannah-Jones.[18][19]

References

  1. ^ "Lisa Jones". Retrieved 19 August 2024.
  2. ^ a b "IUPUI chemist receives $1.1M NSF grant for research, training of minority future researchers: Newscenter: Indiana University–Purdue University Indianapolis". archive.news.iupui.edu. Retrieved 2018-04-22.
  3. ^ @Victoria08Davis, VICTORIA T. DAVIS. "IUPUI chemist awarded more than $1 million for research, training of minority students". Indianapolis Recorder Newspaper. Retrieved 2018-04-22.{{cite news}}: CS1 maint: numeric names: authors list (link)
  4. ^ Jones, Lisa Michelle (4 August 2008). Using Protein Design to Understand the Role of Electrostatic Interactions on Calcium Binding Affinity and Molecular Recognition (PhD). Atlanta, GA: Georgia State University. Retrieved 7 July 2021.
  5. ^ "SoCal MS: Mass Spec Symposium". SoCal MS. Retrieved 7 July 2021.
  6. ^ Maleknia, Simin D.; Ralston, Corie Y.; Brenowitz, Michael D.; Downard, Kevin M.; Chance, Mark R. (2001). "Determination of macromolecular folding and structure by synchrotron x‐ray radiolysis techniques". Analytical Biochemistry. 289: 103–115. doi:10.1006/abio.2000.4910. PMID 11161303.
  7. ^ Jones, Lisa M.; Zhang, Hao; Vidavsky, Ilan; Gross, Michael L. (2010-02-15). "An On-Line, High-Pressure Digestion System for Protein Characterization by Hydrogen/Deuterium Exchange and Mass Spectrometry". Analytical Chemistry. 82 (4): 1171–1174. doi:10.1021/ac902477u. PMC 2826105. PMID 20095571.
  8. ^ "Lisa Jones". stem.indiana.edu. Retrieved 2018-04-22.
  9. ^ Brown, Alex. "IUPUI Professor Receives Lucrative Award". Retrieved 2018-04-22.
  10. ^ "Its official! We're getting FPOP in Baltimore!". proteomicsnews.blogspot.co.uk. 2016-06-11. Retrieved 2018-04-22.
  11. ^ "Professor Lisa Jones - Indiana University" (PDF). University of Toledo. 2014-09-24. Retrieved 2018-04-22.
  12. ^ "Proteomic Mass Spec Assesses Biomolecular Teamwork". Genetic Engineering and Biotechnology News. 2020-05-04. Retrieved 2020-06-12.
  13. ^ "PSC Researcher Awarded Biophysical Society's Junior Faculty Award". University of Maryland School of Pharmacy. 2019-03-06. Retrieved 2020-06-12.
  14. ^ Koch, Denise (July 11, 2017). "UMB's CURE Scholars Program Helps Inner City Kids Get Interested In Science". WJZ CBS Baltimore.
  15. ^ Fanning, Patricia (July 14, 2017). "Science Beckons CURE Scholars in Summer". University of Maryland, Baltimore. Retrieved 2021-02-27.
  16. ^ Reid, Gavin E. (September 2017). "American Society for Mass Spectrometry News and Views" (PDF).
  17. ^ 2016-2017 Annual Report (Report). University of Maryland School of Pharmacy. 2017. p. 40. Retrieved 2021-02-27.
  18. ^ Newsome, Melba (June 7, 2021). "Chemist Lisa Jones withdraws from UNC faculty search over Pulitzer-winning journalist's tenure denial". Chemical & Engineering News. Retrieved 7 July 2021.
  19. ^ Chapin, Josh (5 June 2021). "Highly sought-after chemist turns down job at UNC-CH as Hannah-Jones tenure dispute unfolds". WTVD. Retrieved 7 July 2021.