Liquiritin
Names
IUPAC name
(2S )-4′-(β-D -Glucopyranosyloxy)-7-hydroxyflavan-4-one
Systematic IUPAC name
(2S )-7-Hydroxy-4-(4-{[(2S ,3R ,4S ,5S ,6R )-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)-2,3-dihydro-4H -1-benzopyran-4-one
Other names
Liquiritoside Liquiritigenin-4'-O -glucoside
Identifiers
ChEBI
ChemSpider
UNII
InChI=1S/C21H22O9/c22-9-17-18(25)19(26)20(27)21(30-17)28-12-4-1-10(2-5-12)15-8-14(24)13-6-3-11(23)7-16(13)29-15/h1-7,15,17-23,25-27H,8-9H2/t15-,17+,18+,19-,20+,21+/m0/s1
Key: DEMKZLAVQYISIA-ZRWXNEIDSA-N
InChI=1/C21H22O9/c22-9-17-18(25)19(26)20(27)21(30-17)28-12-4-1-10(2-5-12)15-8-14(24)13-6-3-11(23)7-16(13)29-15/h1-7,15,17-23,25-27H,8-9H2/t15-,17+,18+,19-,20+,21+/m0/s1
Key: DEMKZLAVQYISIA-ZRWXNEIDBX
C1[C@H](OC2=C(C1=O)C=CC(=C2)O)C3=CC=C(C=C3)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O
Properties
C 21 H 22 O 9
Molar mass
418.398 g·mol−1
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
Chemical compound
Liquiritin is the 4'-O -glucoside of the flavanone liquiritigenin . Liquiritin is one of flavone compounds derived from licorice .[ 1]
References
Further reading
Wang J, Wang D, Yu J, Liu C, Li L, Zhang Y (April 2014). "Isolation of liquiritigenin-4'-apiosyl-glucoside and liquiritin from the root of Glycyrrhiza uralensis by high-performance centrifugal partition chromatography" . Journal of Chromatographic Science . 52 (4): 310– 4. doi :10.1093/chromsci/bmt029 . PMID 23552847 .
Cong, Jing Xiang; Wang, Shao Yan; Gao, Hong (2012). "Separation of Liquiritin by Two-Dimensional Liquid Chromatography". Advanced Materials Research . 455– 456: 1232– 1238. doi :10.4028/www.scientific.net/AMR.455-456.1232 . ISSN 1662-8985 . S2CID 135570958 .
Cong J, Lin B (March 2007). "Separation of Liquiritin by simulated moving bed chromatography". Journal of Chromatography A . 1145 (1– 2): 190– 4. doi :10.1016/j.chroma.2007.01.088 . PMID 17289063 .
Ni H, Xu M, Xie K, Fei Y, Deng H, He Q, Wang T, Liu S, Zhu J, Xu L, Yao M (2020). "Liquiritin Alleviates Pain Through Inhibiting CXCL1/CXCR2 Signaling Pathway in Bone Cancer Pain Rat" . Frontiers in Pharmacology . 11 : 436. doi :10.3389/fphar.2020.00436 . PMC 7193085 . PMID 32390832 .
External links