Leibniz-Forschungsinstitut für Molekulare Pharmakologie

Leibniz-Forschungsinstitut für Molekulare Pharmakologie
Established1992
Focuscell biology, chemical biology, neurobiology, structural biology
Director(s)Dorothea Fiedler, Volker Haucke
Budget21 million euros (2012)
Members270
Formerly calledInstitut für Wirkstofforschung, Leibniz-Institut für Molekulare Pharmakologie
AddressCampus Buch, Robert-Roessle-Str. 10, Berlin 13125
Location
Berlin
,
Berlin
,
Germany
Coordinates52°37′28″N 13°30′15″E / 52.624337°N 13.504139°E / 52.624337; 13.504139
Map
Websitewww.leibniz-fmp.de

The Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) is a research institute in the Leibniz Association, focussing on proteins as basic structures of cellular organisms. It is one of the large number of research institutions based in Berlin. The institute is situated on a research campus in Buch, a northern district of Berlin. Legally, the FMP and seven other Leibniz Institutes based in Berlin are represented by the Forschungsverbund Berlin (Research Association of Berlin).

The institute has around 270 employees,[1] including researchers and administrative staff.

Exterior of Leibniz Institute, showing two buildings.
Northern exterior of FMP Berlin in October 2014

Research Areas

The Institute focuses on fundamental research in life sciences, with an interdisciplinary approach based on chemistry and biology. The institute is organized into three departments under the broad umbrella of molecular pharmacology:[2]

Collaborations

The institute has many collaborations with national and international universities and research institutes, as well as businesses. Collaboration partners include:

Funding

The Institute receives core and external funding. The core funding (Grundfinanzierung) is usually split equally between federal and state contributions.[13] In 2012, the institute had a total revenue of 21 million euros, excluding DFG fees.[14]

History

The institute was founded in 1992 as a successor to the "Institut für Wirkstofforschung" (Institute for Active Materials Research, also translated as the Drugs Research Institute), an Institute of the Academy of Sciences of the GDR. The Institut für Wirkstofforschung was founded in 1977 by Peter Oehme, who also served as its first and only director, and had around 230 employees.[15] After the reunification of Germany, scientific institutions underwent a period of readjustment to align those in the former east and west.[16] In 1991, the German Council of Science and Humanities (Wissenschaftsrat) recommended the founding of an institute focused in the area of molecular pharmacology,[15] which led to the establishment of the institute as it is known today.

The institute was originally located in Friedrichsfelde in east Berlin, but moved to its current location in Buch in 2000.

Logo of Leibniz-FMP prior to 2017, showing that the acronym FMP was still used despite the official name not starting with an "F".
Logo of Leibniz-FMP prior to 2017, showing that the acronym FMP was still used despite the official name not starting with an "F".

Since the founding of the institute, it has been a member of the Leibniz Association. The Institute does not have an official English name, and the acronym "FMP" was used heavily. From 2006, the institute was named Leibniz-Institut für Molekulare Pharmakologie (Leibniz Institute for Molecular Pharmacology), though the institute logo still contained the "FMP" acronym. In May 2017, it was renamed back to "Leibniz-Forschungsinstitut für Molekulare Pharmakologie" (Leibniz Research Institute for Molecular Pharmacology).

Directors of the FMP

References

  1. ^ "FMP Berlin: About us". www.leibniz-fmp.de. Retrieved 17 March 2019.
  2. ^ "FMP Berlin: Research Areas". www.leibniz-fmp.de. Retrieved 17 March 2019.
  3. ^ "FMP Berlin: Presynapses come in a packet – Berlin Scientists Identify the Components and Architecture of Neuronal Contact Sites". www.leibniz-fmp.de. FMP Berlin. 31 August 2018. Retrieved 17 March 2019.
  4. ^ "FMP Berlin: A protein for learning". www.leibniz-fmp.de. FMP Berlin. 4 March 2019. Retrieved 17 March 2019.
  5. ^ "FMP Berlin: When Bacteria Build Homes". www.leibniz-fmp.de. FMP Berlin. 4 May 2018. Retrieved 17 March 2019.
  6. ^ "FMP Berlin: How a Mutated Gene Triggers Hypertension". www.leibniz-fmp.de. FMP Berlin. 4 April 2018. Retrieved 17 March 2019.
  7. ^ Due, Anne V.; Kuper, Jochen; Geerlof, Arie; Kries, Jens Peter von; Wilmanns, Matthias (1 March 2011). "Bisubstrate specificity in histidine/tryptophan biosynthesis isomerase from Mycobacterium tuberculosis by active site metamorphosis". Proceedings of the National Academy of Sciences. 108 (9): 3554–3559. Bibcode:2011PNAS..108.3554D. doi:10.1073/pnas.1015996108. ISSN 0027-8424. PMC 3048130. PMID 21321225.
  8. ^ a b c d e Otten, Cécile; Knox, Jessica; Boulday, Gwénola; Eymery, Mathias; Haniszewski, Marta; Neuenschwander, Martin; Radetzki, Silke; Vogt, Ingo; Hähn, Kristina (4 September 2018). "Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations". EMBO Molecular Medicine. 10 (10): e9155. doi:10.15252/emmm.201809155. ISSN 1757-4684. PMC 6180302. PMID 30181117.
  9. ^ Kesten, Christopher; Wallmann, Arndt; Schneider, René; McFarlane, Heather E.; Diehl, Anne; Khan, Ghazanfar Abbas; van Rossum, Barth-Jan; Lampugnani, Edwin R.; Szymanski, Witold G. (20 February 2019). "The companion of cellulose synthase 1 confers salt tolerance through a Tau-like mechanism in plants". Nature Communications. 10 (1): 857. Bibcode:2019NatCo..10..857K. doi:10.1038/s41467-019-08780-3. ISSN 2041-1723. PMC 6382854. PMID 30787279.
  10. ^ "FMP Berlin: "Salt Prince" CC1: Newly discovered protein has important function in plants - and could also be important for Alzheimer's research". www.leibniz-fmp.de. FMP Berlin. 18 February 2019. Retrieved 17 March 2019.
  11. ^ Wang, Haibin; Lo, Wen-Ting; Vujičić Žagar, Andreja; Gulluni, Federico; Lehmann, Martin; Scapozza, Leonardo; Haucke, Volker; Vadas, Oscar (19 July 2018). "Autoregulation of Class II Alpha PI3K Activity by Its Lipid-Binding PX-C2 Domain Module". Molecular Cell. 71 (2): 343–351.e4. doi:10.1016/j.molcel.2018.06.042. PMID 30029007.
  12. ^ "FMP Berlin: Cooperations (Kuehne group)". www.leibniz-fmp.de. Retrieved 17 March 2019.
  13. ^ Projektträger, Redaktion: DLR. "Grundfinanzierung der Forschungseinrichtungen - BuFI Kampagne". Bundesbericht Forschung und Innovation - BuFI Kampagne (in German). Retrieved 17 March 2019.
  14. ^ Stellungnahme zum Leibniz-Institut für Molekulare Pharmakologie (FMP) im Forschungsverbund Berlin e. V (PDF) (Report) (in German and English). Evaluation Committee of the Leibniz Association. 27 November 2014. Retrieved 17 March 2019.
  15. ^ a b Stellungnahmen zu den außeruniversitären Forschungseinrichtungen in der ehemaligen DDR auf dem Gebiet der Biowissenschaften und der Medizin | Institut für Wirkstofforschung (IWF), Berlin (PDF) (Report) (in German). Vol. 335/91. Wissenschaftsrat. July 1991. pp. 41–49. Retrieved 17 March 2019.
  16. ^ "East German scientists faced opportunities and disappointment during reunification | DW | 28.09.2010". www.dw.com. Deutsche Welle. Retrieved 17 March 2019.
  17. ^ "FMP Berlin: Hartmut Oschkinat - Curriculum Vitae". www.leibniz-fmp.de. Retrieved 17 March 2019.
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52°37′28″N 13°30′15″E / 52.624337°N 13.504139°E / 52.624337; 13.504139