Karl Wieghardt

Karl Weighardt
Born (1942-07-25) July 25, 1942 (age 82)
NationalityGerman
Alma materHeidelberg University
Scientific career
FieldsInorganic Chemistry, Coordination Chemistry, Bioinorganic Chemistry
InstitutionsMax Planck Institute for Bioinorganic Chemistry

Ruhr University Bochum
TU Hannover
University of Leeds

Heidelberg University
Doctoral advisorHans Siebert
Other academic advisorsA. Geoffrey Sykes
Doctoral studentsKarsten Meyer, Carsten Krebs
Other notable studentsJohn Berry (postdoc), Connie C. Lu (postdoc)

Karl Wieghardt (born 25 July 1942, in Göttingen) is a German inorganic chemist and emeritus director of the Max Planck Institute for Chemical Energy Conversion in Mülheim. He was active in the preparation and detailed characterization of models for iron and manganese metalloenzymes, metal complexes of noninnocent ligands, and magnetic interactions in polynuclear metal complexes.

Early life and education

Wieghardt was born in 1942 in Göttingen, Germany, the son of the physicist Karl Wieghardt and grandson of the mathematician also named Karl Wieghardt.[1] From 1947-1952, Wieghardt lived in England as his father was working at the Admiralty Research Laboratory of the British Navy in Teddington.[1] While in the UK, he attended elementary school in Elstead, Surrey.[1] Following the nuclear espionage affair surrounding Klaus Fuchs, Wieghardt's father was dismissed from the Admiralty Research Laboratory, and he moved his family back to Germany.[1] At the age of 12, Wieghardt obtained a chemistry kit as a Christmas present from his parents, then proceeded to set his basement on fire. His parents then forbade him from doing or studying chemistry for the next eight years.[2] In 1962, Wieghardt graduated from the Johanneum secondary school in Hamburg.

Wieghardt then attended Heidelberg University, where he studied chemistry.[1] Wieghardt obtained his PhD in 1969 at Heidelberg University with Prof. Hans Siebert.[3][4] His dissertation involved the x-ray structure analysis of multinuclear complexes of cobalt(III).[1][5][6] He then conducted postdoctoral studies with Prof. A. Geoffrey Sykes, FRS at the University of Leeds, where he studied the kinetics and reaction mechanisms of electron transfer processes in binuclear cobalt complexes.[7][8][9][10][11]

Independent career

Structure of OTi(NCS)2(Me3tacn), first example of a titanyl complex as described by the Wieghardt group.[12]

Wieghardt returned to Germany, and completed his habilitation at the University of Heidelberg in 1975 with a thesis on the structural chemistry and mechanistic investigations on polynuclear cobalt-amine complexes.[1] At the end of 1975, he was hired as an associate professor at the Technical University of Hannover.[1] His work there focused on the synthesis, reactions and reaction mechanisms of vanadium and molybdenum complexes with hydroxylamine and hydroxylamine derivatives as ligands.[1] In 1981 he moved to the Ruhr University Bochum as professor. It was at this stage of his career that he expanded the size of his research group, and moved into the field of bioinorganic chemistry, synthesizing transition metal complexes that act as analogs for metalloprotein active sites.[2][13][14] Wieghardt went on to popularize the utility of 1,4,7-triazacyclononane and its derivatives as ligands for biomimetic transition metal complexes.[15][16] In 1994, he was appointed Director of the Max Planck Institute for Bioinorganic Chemistry. While at the Max Planck Institute, he developed a research program to study complexes of noninnocent ligands.[17] Since 2010, he has been professor emeritus.[18]

Research highlights

  • Coordination compounds with coordinated tyrosyl radicals as galactose oxidase mimics[19][20]
  • Double-exchange in a molecular diiron complex[21]
  • High-valent iron(V) and iron(VI) complexes[22][23]

Awards

References

  1. ^ a b c d e f g h i "Wer ist's?: Karl Weighardt". Nachrichten aus Chemie, Technik und Laboratorium. 44 (3): 316–317. 1996. doi:10.1002/nadc.19960440330. ISSN 1868-0054.
  2. ^ a b Voices of Inorganic Chemistry - Karl Weighardt, retrieved 2021-05-17
  3. ^ Wieghardt, K.; Siebert, H. (1970). "μ-Nitro-di-μ-hydroxo-bis[trinitro-kobaltat(III)]-Komplexe". Zeitschrift für anorganische und allgemeine Chemie (in German). 374 (2): 186–190. doi:10.1002/zaac.19703740207. ISSN 1521-3749.
  4. ^ Wieghardt, K.; Siebert, H. (1971). "Zur Kenntnis der Hexafluoromanganate(III)". Zeitschrift für anorganische und allgemeine Chemie (in German). 381 (1): 12–20. doi:10.1002/zaac.19713810103. ISSN 1521-3749.
  5. ^ Weiss, J.; Siebert, H.; Wieghardt, K. (1970-11-15). "Die Kristall- und Molekülstruktur von [Co3(NH3)8(OH)2(NO2)2(CN)2](ClO4)3.NaClO4.2H2O". Acta Crystallographica Section B: Structural Crystallography and Crystal Chemistry (in German). 26 (11): 1709–1712. doi:10.1107/S0567740870004776. ISSN 0567-7408.
  6. ^ Wieghardt, K.; Weiss, J.; Siebert, H. (1971). "Die Molekül- und Kristallstruktur von [Co3(CN)2 (OH)4 (NH3)8][Co2(NO2)6 (OH)2, NO2] · H2O". Zeitschrift für anorganische und allgemeine Chemie (in German). 383 (2): 151–157. doi:10.1002/zaac.19713830207. ISSN 1521-3749.
  7. ^ Richens, David T. (2008-03-15). "A tribute to Alfred Geoffrey (Geoff) Sykes FRS (1934–2007)". Polyhedron. 27 (4): 1139–1140. doi:10.1016/j.poly.2007.12.009. ISSN 0277-5387.
  8. ^ Scott, K. L.; Wieghardt, K.; Sykes, A. G. (1973-03-01). ".mu.-Oxalato-cobalt(III) complexes". Inorganic Chemistry. 12 (3): 655–663. doi:10.1021/ic50121a034. ISSN 0020-1669.
  9. ^ Jentsch, Walther.; Schmidt, Wilfried.; Sykes, A. Geoffrey.; Wieghardt, Karl. (1977-08-01). "Reaction sequence in the hydroxo-bridge cleavage of the tri-.mu.-hydroxo-bis[triamminecobalt(III)] complex. Identification of an isomerization step". Inorganic Chemistry. 16 (8): 1935–1937. doi:10.1021/ic50174a020. ISSN 0020-1669.
  10. ^ Wieghardt, Karl; Sykes, A. Geoffrey (1974-01-01). "The Cr2+ and V2+ reduction of μ-carboxylato-dicobalt(III) ammine complexes. Part III. The mechanism of reduction of μ-benzoato- and μ-o-chlorobenzoato-complexes". Journal of the Chemical Society, Dalton Transactions (6): 651–654. doi:10.1039/DT9740000651. ISSN 1364-5447.
  11. ^ Edwards, Julian D.; Wieghardt, Karl; Sykes, A. Geoffrey (1974-01-01). "Reactions of μ-hydroxo-dicobalt(III) complexes. Part XII. Equilibrium and kinetic studies on hydroxo-bridge cleavage reactions of two triply-bridged dicobalt(III) complexes in aqueous perchloric acid solutions". Journal of the Chemical Society, Dalton Transactions (20): 2198–2204. doi:10.1039/DT9740002198. ISSN 1364-5447.
  12. ^ Axel Bodner; Peter Jeske; Thomas Weyhermueller; Karl Wieghardt; Erich Dubler; Helmut Schmalle; Bernhard Nuber (1992). "{Mono- and Dinuclear Titanium(III)/Titanium(IV) Complexes with 1,4,7-Trimethyl-1,4,7-triazacyclononane (L). Crystal Structures of a Compositionally Disordered Green and a Blue Form of [LTiCl3]. Structures of [LTi(O)(NCS)2], [LTi(OCH3)Br2](ClO4), and [L2Ti2(O)2F2(mu-F)](PF6)". Inorganic Chemistry. 31 (18): 3737–3748. doi:10.1021/ic00044a015.
  13. ^ Wieghardt, Karl; Pohl, Klaus; Gebert, Walter (1983). "[(C6H15N3)Fe2(μ-O)(μ-CH3CO2)2]2+ a Dinuclear Iron, (III)Complex with a Metazidohemerythrin-Type Structure". Angewandte Chemie International Edition in English. 22 (9): 727. doi:10.1002/anie.198307271. ISSN 1521-3773.
  14. ^ Chaudhury, Phalguni; Wieghardt, Karl; Nuber, Bernhard; Weiss, Johannes (1985). "[L2Fe(μ-OH)(μ-CH3CO2)2](ClO4)·H2O, a Model Compound for the Diiron Centers in Deoxyhemerythrin". Angewandte Chemie International Edition in English. 24 (9): 778–779. doi:10.1002/anie.198507781. ISSN 1521-3773.
  15. ^ Chaudhuri, P.; Wieghardt, K. (1987). "The Chemistry of 1,4,7-Triazacyclononane and Related Tridentate Macrocyclic Compounds". In Lippard, Stephen J. (ed.). Progress in Inorganic Chemistry. Vol. 35. Hoboken, NJ, USA: John Wiley & Sons, Inc. pp. 329–436. doi:10.1002/9780470166369.ch4. ISBN 978-0-470-16636-9.
  16. ^ Weighardt, Karl (1988). "1,4,7-Triazacyclononane and N,N',N"-Trimethyl-1,4,7-triazacyclononane - Two Versatile Macrocycles for the Synthesis of Monomeric and Oligomeric Metal Complexes". Pure and Applied Chemistry. 60 (4): 509–16. doi:10.1351/pac198860040509. S2CID 96871622.
  17. ^ Bart, S.C.; Chlopek, K.; Bill, E.; Bouwkamp M.W.; Lobkovsky, E.; Nesse, F.; Weighardt, K.; Chirik, P. J. (2006). "Electronic Structure of Bis(imino)pyridine Iron Dichloride, Monochloride, and Neutral Ligand Complexes: A Combined Structural, Spectroscopic, and Computational Study". J. Am. Chem. Soc. 128 (42): 13901–13912. doi:10.1021/ja064557b. PMID 17044718.
  18. ^ "MPI für chemische Energiekonversion: Prof. Dr. Karl Wieghardt: Vita". www.cec.mpg.de. Retrieved 2016-10-05.
  19. ^ Adam, Britta; Bill, Eckhard; Bothe, Eberhard; Goerdt, Beatrix; Haselhorst, Gabriele; Hildenbrand, Knut; Sokolowski, Achim; Steenken, Steen; Weyhermüller, Thomas; Wieghardt, Karl (1997). "Phenoxyl Radical Complexes of Gallium, Scandium, Iron and Manganese". Chemistry – A European Journal. 3 (2): 308–319. doi:10.1002/chem.19970030221. ISSN 1521-3765. PMID 24022963.
  20. ^ Chaudhuri, Phalguni; Hess, Martina; Flörke, Ulrich; Wieghardt, Karl (1998). "From Structural Models of Galactose Oxidase to Homogeneous Catalysis: Efficient Aerobic Oxidation of Alcohols". Angewandte Chemie International Edition. 37 (16): 2217–2220. doi:10.1002/(SICI)1521-3773(19980904)37:16<2217::AID-ANIE2217>3.0.CO;2-D. ISSN 1521-3773. PMID 29711456.
  21. ^ Drüeke, S.; Chaudhuri, P.; Pohl, K.; Wieghardt, K.; Ding, X.-Q.; Bill, E.; Sawaryn, A.; Trautwein, A. X.; Winkler, H.; Gurman, S. J. (1989-01-01). "The novel mixed-valence, exchange-coupled, class III dimer [L2Fe2(μ-OH)3]2+(L =N,N′,N"-trimethyl-1,4,7-triazacyclononane)". Journal of the Chemical Society, Chemical Communications (1): 59–62. doi:10.1039/C39890000059. ISSN 0022-4936.
  22. ^ Meyer, Karsten; Bill, Eckhard; Mienert, Bernd; Weyhermüller, Thomas; Wieghardt, Karl (1999-05-01). "Photolysis of cis- and trans-[FeIII(cyclam)(N3)2]+ Complexes: Spectroscopic Characterization of a Nitridoiron(V) Species". Journal of the American Chemical Society. 121 (20): 4859–4876. doi:10.1021/ja983454t. ISSN 0002-7863.
  23. ^ Berry, John F.; Bill, Eckhard; Bothe, Eberhard; George, Serena DeBeer; Mienert, Bernd; Neese, Frank; Wieghardt, Karl (2006-06-30). "An Octahedral Coordination Complex of Iron(VI)". Science. 312 (5782): 1937–1941. Bibcode:2006Sci...312.1937B. doi:10.1126/science.1128506. ISSN 0036-8075. PMID 16741074. S2CID 42631402.
  24. ^ "ACS Award in Inorganic Chemistry". American Chemical Society. Retrieved 2021-05-17.